dawn phenomenon


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dawn phe·nom·e·non

abrupt increases in fasting levels of plasma glucose concentrations between 5 and 9 AM, in the absence of antecedent hypoglycemia; occurs in diabetic patients receiving insulin therapy.
Early morning hyperglycemia not preceded by hypoglycemia, linked to increased insulin requirements in type 1 DM, possibly due to nocturnal pulses of hGH; DP also occurs in insulin-pump users receiving continuous subcutaneous insulin infusion who are presumed to be euglycemic. The phenomenon is attributed to residual endogenous insulin or insulin-like molecules

dawn phenomenon

Diabetology Early morning hyperglycemia not preceded by hypoglycemia, linked to ↑ insulin requirements in type 1 DM, possibly due to nocturnal pulses of hGH; DP also occurs in insulin-pump users receiving continuous subcutaneous insulin infusion, who are presumed to be euglycemic; DP is attributed to residual endogenous insulin or insulin-like molecules. Cf Somogyi phenomenon, Subcutaneous insulin resistance syndrome.

dawn phe·nom·e·non

(dawn fĕ-nom'ĕ-non)
Abrupt increases in fasting levels of plasma glucose concentrations between 5-9 am in the absence of antecedent hypoglycemia; occurs in diabetic patients receiving insulin therapy.

dawn phenomenon

A sharp rise in the blood sugar level in the early morning in insulin-dependent diabetics. The rise is thought to be caused by nocturnal growth hormone secretion.
References in periodicals archive ?
Owens, "Magnitude of the dawn phenomenon and its impact on the overall glucose exposure in type 2 diabetes: is this of concern?" Diabetes Care, vol.
Schade, "Frequency of the dawn phenomenon in type 2 diabetes: implications for diabetes therapy," Diabetes Technology & Therapeutics, vol.
Ho, "Effect of growth hormone on dawn phenomenon in patients with type 2 diabetes," Growth Factors, vol.
Shan et al., "Association between sleep disorders and dawn phenomenon in patients with type 2 diabetes mellitus," Zhonghua Yi Xue Za Zhi, vol.
Fanelli, "Thirty years of research on the dawn phenomenon: lessons to optimize blood glucose control in diabetes," Diabetes Care, vol.
Saitou et al., "Nocturnal blood glucose and IGFBP-1 changes in type 1 diabetes: differences in the dawn phenomenon between insulin regimens," Experimental and Clinical Endocrinology & Diabetes, vol.
Wang et al., "Correlation study between obesity and dawn phenomenon in patients with type 2 diabetes," Zhonghua Nei Ke Za Zhi, vol.