Language Deficits as a Preclinical Window into Parkinson's Disease: Evidence from Asymptomatic Parkin and Dardarin
Lynch et al., "Mutations in the gene LRRK2 encoding dardarin
(PARK8) cause familial Parkinson's disease: clinical, pathological, olfactory and functional imaging and genetic data," Brain, vol.
The LRRK2 gene codes for a multidomain protein known as dardarin
, which has been linked to play an integral role in signaling pathways that are significant for neuron tunctioning as well as protein-protein signaling (Nuytemans et al., 2010).