dardarin

(dar-dar'u) [Basque dardara, tremor]

A protein whose presence in the body has been associated with an autosomal dominant (familial) form of Parkinson's disease.

Synonym: leucine-rich repeat kinase 2

Mentioned in ?

Parkinson's disease

References in periodicals archive ?

Lynch et al., "Mutations in the gene LRRK2 encoding dardarin (PARK8) cause familial Parkinson's disease: clinical, pathological, olfactory and functional imaging and genetic data," Brain, vol.

LRRK2 G2019S Mutation: Prevalence and Clinical Features in Moroccans with Parkinson's Disease

The LRRK2 gene codes for a multidomain protein known as dardarin, which has been linked to play an integral role in signaling pathways that are significant for neuron tunctioning as well as protein-protein signaling (Nuytemans et al., 2010).

Understanding Parkinson Disease: a complex and multifaceted illness

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