DACT1(redirected from dapper, antagonist of beta-catenin, homolog 1)
DACT1A gene on chromosome 14q23.1 that encodes a protein which upregulates DVL2-mediated signalling pathways during development. DACT1 binds to DVL2 and impedes CTNNB1/beta-catenin degradation, thereby enhancing transcriptional activation of target genes of the Wnt signalling pathway.
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