danthron

danthron

[dan′thron]
a stimulant laxative. Products containing danthron are no longer available in the United States since it was found to be carcinogenic in animal models.

danthron

Dantron, a stimulant laxative. A brand name is Capsuvac.

danthron

a by-product of the dye industry used as a purgative, especially in horses. Called also dihydroxyanthraquinone. Veterinary practice with horses has veered away from these relatively violent purges and depends on mineral oil or liquid paraffin to treat constipation.
References in periodicals archive ?
Danthron, an anthraquinone derivative, induces DNA damage and caspase cascades-mediated apoptosis in SNU-1 human gastric cancer cells through mitochondrial permeability transition pores and Bax-triggered pathways.
Genotoxicity of the laxative drug components emodin, aloe-emodin and danthron in mammalian cells: topoisomerase II mediated?
That has only happened three times in the past 25 years: in 1977 with the antimicrobial hexachlorophene, in 1979 with the antihistamine methapyrilene and in 1978 with the laxative danthron.
Danthron induces DNA damage and inhibits DNA repair gene expressions in GBM 8401 human brain glioblastoma multiforms cells.
That happened in 1977 with the antimicrobial hexachlorophene, two years later with the antihistamine methapyrilene and again in 1987 with danthron, a laxative.