DDB1(redirected from damage-specific DNA binding protein 1, 127kDa)
DDB1A gene on chromosome 11q12-q13 that encodes the large subunit of DNA damage-binding protein (a heterodimer composed of a large and a small (DDB2) subunit) that functions in nucleotide-excision repair.
DDB1 mutations have been tentatively linked xeroderma pigmentosum complementation group E (XPE).
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.