d-penicillamine


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Related to d-penicillamine: Cuprimine

penicillamine, d-penicillamine

a product of penicillin which chelates copper and other metals; used in the treatment of copper accumulation associated with chronic hepatitis, copper-associated hepatopathy of Bedlington terriers, and lead poisoning.
References in periodicals archive ?
Adverse effects of reduced-dose D-Penicillamine in children with mild-to-moderate lead poisoning.
Effect of lead intoxication and D-penicillamine treatment on hematological indices in rats.
Oral d-penicillamine and intramuscular BAL + EDTA in the treatment of lead accumulation.
Cognitive P300 fields in an organic psychosyndrome (Wilson's disease) before and during treatment with d-penicillamine.
Serial changes of cranial computerized tomographic findings in Wilson disease during d-penicillamine therapy.
Program: Take 500 mg (2 capsules of 250 mg each) D-penicillamine or N-acetyl-D-penicillamine with each meal and before bed for 3 days.
This short course of D-penicillamine avoids the rare side effects of longer-term therapeutic doses of the drug.
For more than modest amounts, alternate day D-penicillamine for 30 to 60 days with supplemental calcium, magnesium, and zinc on the other days to replace these minerals, which penicillamine will chelate along with the other divalent (double-charged) heavy metals.
D-penicillamine provocation tests for nutritional and toxic minerals revealed a deficit in magnesium and an excess of arsenic and lead.
D-penicillamine provocation showed the magnesium deficit had been corrected and that lead and arsenic were no longer detectable although increase in cadmium excretion was observed and detoxification continued for another six months.
ASIMP working group on toxic minerals, d-penicillamine protocol (based on Jaffe) for determining toxic and nutritional mineral status by provocation into the urine.
d-pen = d-penicillamine provocative tests for essential and toxic minerals.