d-glucose 6-phosphate

d-·glu·cose 6-phos·phate

(glū'kōs fos'fāt),
A key intermediate in processes such as glycolysis, glycogenolysis, and pentose phosphate shunt; elevated levels inhibit brain hexokinase and glycolysis.
Farlex Partner Medical Dictionary © Farlex 2012


Robert, English chemist, 1884-1941.
Robison ester - a key intermediate in glycolysis, glycogenolysis, pentose phosphate shunt, etc. Synonym(s): D-glucose 6-phosphate; Robison-Embden ester
Robison ester dehydrogenase - a deficiency of this enzyme can lead to severe hemolytic anemia and favism. Synonym(s): glucose 6-phosphate dehydrogenase
Robison-Embden ester - Synonym(s): Robison-ester
Medical Eponyms © Farlex 2012
Mentioned in ?
References in periodicals archive ?
This was performed according to the CLSI (2006), using disks containing 200 [micro]g/mL of fosfomycin added to 50 [micro]g/mL of D-glucose 6-phosphate (Cecon, Sao Paulo, Brazil).
Sugar phosphates, such as d-glucose 6-phosphate (glu6P), [3] play a role as intermediary metabolites in several metabolic pathways, including glycolysis, gluconeogenesis, and the pentose phosphate pathway (PPP).
[3] Nonstandard abbreviations: glu-6P, d-glucose 6-phosphate; PPP, pentose phosphate pathway; TALDO, transaldolase; LC-MS/MS, liquid chromatography with tandem mass spectrometry; DHAP, dihydroxyacetone phosphate; ery-4P, D-erythrose 4-phosphate; fru-6P, D-fructose 6-phosphate; gly-3P, D,l-glyceraldehyde 3-phosphate; ribo-5P, d-ribose 5-phosphate; ribu-5P, d-ribulose 5-phosphate; sed-7P, D-sedoheptulose 7-phosphate; xylu-5P, D-xylulose 5-phosphate; ACN, acetonitrile; IS, internal standard; and MRM, multiple reaction monitoring (mode).
The basic idea of using GALT to assess Gal-1-P in erythrocytes was extended to measuring the product of the reaction, [alpha]-D-glucose 1-phosphate (Glu-1-P), after enzymatic conversion to D-glucose 6-phosphate (Glu-6-P) and treatment with Glu-6-P dehydrogenase to form NADH, which was measured fluorometrically (8), or by determining the radioisotope content of the Glu-1-P when [sup.14]C-labeled UDPG was a substrate in the reaction (9).