cytotoxin


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cytotoxin

 [si´to-tok″sin]
a toxin having a specific toxic action on cells of special organs.

cy·to·tox·in

(sī'tō-tok'sin),
A specific substance, which may or may not be an antibody, that inhibits or prevents the functions of cells, causes destruction of cells, or both.
See also: perforin.
[cyto- + G. toxikon, poison]

cytotoxin

/cy·to·tox·in/ (si´to-tok″sin) a toxin or antibody having a specific toxic action upon cells of special organs.

cytotoxin

(sī′tə-tŏk′sĭn)
n.
A substance having a specific toxic effect on certain cells.

cytotoxin

[sī′tōtok′sin]
Etymology: Gk, kytos + toxikon, poison
a substance that has a toxic effect on certain cells. An antibody may act as a cytotoxin. cytotoxic, adj.

cy·to·tox·in

(sī'tō-tok'sin)
A specific substance (which may or may not be an antibody) that inhibits or prevents the functions of cells, causes destruction of cells, or both.
[cyto- + G. toxikon, poison]

cytotoxin

an agent toxic to CELLS, that is, capable of damaging or destroying them.

cytotoxin

a toxin having a specific toxic action on cells of special organs.
References in periodicals archive ?
cholerae and Helicobacter pylori are known for their ability to produce vacuolating cytotoxins demonstrating the association between biological effects (vacuolation) and pathogenicity caused by these microorganisms.
From this venom the purification and the primary structure of two short neurotoxins and of 14 cytotoxins have been reported.
032 * SE, standard error; WBC, white blood cell count; LY%, lymphocyte count percentage; MO%, monocytes count percentage; MC (%), rate of cytotoxin in monocyte; [CD4.
Overexpressed cell surface interleukin-4 receptor molecules can be successfully targeted for antitumor cytotoxin therapy.
TABLE 1 Lab tests for C difficile infection Test Substance detected Time needed Cytotoxin Toxin B 1-3 d Toxin culture Toxigenic C difficile ([dagger]) 3-5 d EIA toxin A or A/B Toxin A or A/B Hours EIA GDH * C difficile Hours EIA GDH * and C difficile and Hours toxin A/B C difficile toxin RT-PCR Toxigenic C difficile ([dagger]) Hours Test Sensitivity Specificity Cytotoxin 95% 90%-95% Toxin culture >95% 80%-90% EIA toxin A or A/B 75%-80% 97%-98% EIA GDH * 95%-100% 70%-80% EIA GDH * and 95%-100% 97%-98% toxin A/B RT-PCR >98% 80%-99% * GDH is the common C difficile antigen.
7 The historic laboratory test for diagnosis of CDI was the cell cytotoxin assay; however, most clinical laboratories have switched to an enzyme immunoassay kit to detect both major C.
Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori: association of specific vacA types with cytotoxin production and peptic ulceration.
The production of heat-labile cytotoxin is not restricted to E.
Yissum Research Company of the Hebrew University of Jerusalem (Israel) has patented a new approach for the therapy of allergic responses, based on targeted elimination of cells expressing the FcRI receptor by a chimeric cytotoxin Fc2-3-PE40.
She said she was undergoing a six-week cytotoxin treatment ahead of chemotherapy and would be undergoing a bone marrow transplant once a suitable donor was found.
In May 2002, she got a dose of a drug called IL13-PE38QQR Cytotoxin, or IL13-toxin for short.