cytotoxic drug


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cytotoxic drug

Oncology An anticancer drug which acts by killing or preventing the cell division Adverse effects Damage to noncancerous tissues or organs with a high proportion of actively dividing cells–eg, BM, hair follicles, GI tract, thereby limiting the amount and frequency of drug administration. See Chemotherapy.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
* designating a cytotoxic drug administration area, which only permits entry to authorised people.
"HPAPIs and Cytotoxic Drugs Manufacturing Market, (2nd Edition), 2016-2026." March 9, 2016.
He also will oversee the company's potent and cytotoxic drug development services, which include a dedicated and segregated potent facility.
Cascone previously served as director of potent pharmaceutical development, managing the company's potent and cytotoxic drug handling capabilities as well as its dedicated and segregated potent facility.
He previously served as director of potent pharmaceutical development, managing Metrics' potent and cytotoxic drug handling capabilities as well as its dedicated and segregated potent facility.
The SNAP platform offers a simple, chemically-driven approach for linking any anti-cancer antibody with small molecule cytotoxic drug to deliver ADCs with maximised and uniform ratios of drug to antibody.
GRN1005 is the firm's lead LRP-directed peptide-drug conjugate (LRP-directed PDC) that consists of the cytotoxic drug, paclitaxel, linked to a peptide (Angiopep-2) that targets the LRP receptor to cross the blood-brain barrier (BBB) and to target tumours in the brain.
This increased survival rate is relevant compared to the 54.5% rate observed in patients with the current standard of care (usually transarterial chemoembolisation with a cytotoxic drug).
It is only recently that ADC's true potentials were fully tapped, thanks to the significant advances in linker engineering, conjugation technologies and continuous development of highly potent cytotoxic drugs.
Antibody Fragment-Drug Conjugates (FDCs, also called immuno-conjugates) combine the pharmacological potency of highly cytotoxic drugs with the high specificity of an antibody against tumour-associated targets.
Based on drug types, global anticancer drugs market is segmented into cytotoxic drugs, targeted drugs, and hormonal drugs.

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