cytotoxic agent


Also found in: Dictionary, Thesaurus, Legal, Financial, Encyclopedia.
Related to cytotoxic agent: cytotoxic drugs, Cytotoxins

cytotoxic agent

A drug that destroys cells or prevents them from multiplying. Cytotoxic agents are used to treat cancers and severe immunological disorders, e.g., vasculitis, some forms of glomerulonephritis. An ideal agent would destroy proliferating cells without injuring the normal cells of the body.
See also: agent
References in periodicals archive ?
When inotuzumab ozogamicin binds to the CD22 antigen on B-cells, it is internalized into the cell, where the cytotoxic agent calicheamicin is released to destroy the cell.
The company has patented the cytotoxic agent Disorazol Z in 35 countries, including the United States, Japan, Europe, China, Russia, Korea and Taiwan.
The administration of cytotoxic agents may be required for patients in critical care areas.
Cytotoxic agents help kill cancer cells or stop them from multiplying, making them applicable in almost every cancer type.
arjuna as part of a drug discovery program for cytotoxic agents from Indian medicinal plants.
DCDS4501A is an ADC consisting of an anti-CD79b monoclonal antibody conjugated to the cytotoxic agent MMAE using Seattle Genetics' ADC technology.
ADC's are molecules composed of a tumour specific monoclonal antibody connected to a cytotoxic agent.
The last patient has been treated with the company's proprietary photosensitiser Amphinex used in combination with the cytotoxic agent bleomycin at University College Hospital (UCH) in London.
c) Arjunic acid in Terminalia is a less active cytotoxic agent than vinblastine.
Clavis Pharma, Oslo, (OSE: CLAVIS) has reached an important milestone in its haematology program with Elacyt, its novel cytotoxic agent.
Super-Leu-Dox incorporates the TAP technology, comprising a four-amino acid peptide conjugated to a cytotoxic agent whose activity is inhibited when it is conjugated to the peptide.