Functionally inert HIV-specific cytotoxic T lymphocytes
do not play a major role in chronically infected adults and children.
Memory and distribution of virus-specific cytotoxic T lymphocytes
(CTLs) and CTL precursors after rotavirus infection.
There are data on the possibility of the involvement of the DNase activity of T-lymphocytes not only in the DNA fragmentation induced by cytotoxic T lymphocytes
(CTL) to target cells, but also in the process of programmed death of type 1 of these cytotoxic cells (CTL).
The product is a 'prime-boost' cancer immunotherapy product aimed to synergistically induce and expand in vivo cytotoxic T lymphocytes
targeting NY-ESO-1 - found in a broad set of tumours.
Our data suggest that individuals who were infected with seasonal human influenza A viruses previously or who received seasonal human influenza vaccines may derive benefit, at least in part, from the preexisting cross-reactive memory cytotoxic T lymphocytes
to reduce the severity of pdmH1N1 infection even without protective antibodies," said the researchers.
Heterosubtypic immunity to influenza A virus infection requires B cells but not CDS+ cytotoxic T lymphocytes
ALVAC-HIV induces the proliferation of cytotoxic T lymphocytes
and contains genes coding for glycoprotein 120 and other HIV components in a canarypox vector.
Studying a dozen people with HIV, the scientists found that those who progressed quickest to AIDS had relatively few virus-killing immune cells, known as cytotoxic T lymphocytes
, that recognize Tat.
The evidence demonstrates that Defibrotide has anti-inflammatory activity because it prevents transendothelial migration of immune effector cells, and it can reduce the chemotherapy-induced antigenicity of endothelial cells towards allogeneic cytotoxic T lymphocytes
Some of the most promising approaches among therapeutic vaccines prompt cytotoxic T lymphocytes
to control HIV infection.
Cytotoxic T lymphocytes
, or CTLs, richly deserve their nickname--killer cells.
CytoDyn's CRO, will present Phase I/II data demonstrating the antiviral effects and absence of liver toxicity in individuals who have failed Highly Active Antiretroviral Therapy (HAART) after Cytolin(R) was used to protect CD4+ T lymphocytes from the anti-self, anti-CD4 cytotoxic T lymphocytes
that proliferate uniquely in humans infected with HIV.