cytotoxic

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cytotoxic

having destructive action on cells, usually only certain types of cells; see cytotoxicity.

cy·to·tox·ic

(sī'tō-tok'sik),

Detrimental or destructive to cells.

cytotoxic

(sī′tə-tŏk′sĭk)

adj.

Of, relating to, or producing a toxic effect on cells.

cy′to·tox·ic′i·ty (-tŏk-sĭs′ĭ-tē) n.

cytotoxic

See cytotoxin.

cy·to·tox·ic

(sī'tō-tok'sik)

Detrimental or destructive to cells; pertaining to the effect of noncytophilic antibody on specific antigen, frequently, but not always, mediating the action of complement.

cytotoxic

cell-destructive, e.g. antibody-antigen reaction, usually involving complement activation

cy·to·tox·ic

(sī'tō-tok'sik)

Detrimental or destructive to cells.

cytotoxic

having a deleterious effect upon cells.

cytotoxic antibody

see cytotoxic antibody.

cytotoxic drugs

generally refers to those used in chemotherapy of neoplasms, e.g. cyclophosphamide, vincristine, etc.

cytotoxic T lymphocyte

see T lymphocyte.

References in periodicals archive ?

Prime screening of the extract through cytotoxic activity provides useful information about the antitumor and anticancer activity for the future use of the medicinal plants extract.

Short Communication - CYTOTOXIC, ANTIOXIDANT, ANTIMICROBIAL ACTIVITIES OF METHONOL CRUDE EXTRACTS OF CARDIA OBALIQUA (LINN.)

Our approved Safebridge Category 4, GMP facility in Lugano was designed to accommodate the complex processes needed for production of very potent active ingredients including cytotoxics like ADCs.

CMC Biologics, IDT Biologika expand ADC alliance

The report reviews Cytotoxic T-Lymphocyte Protein 4 (CTLA-4 or CD152) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources

Cytotoxic T-Lymphocyte Protein 4 (CTLA-4 or CD152) - Pipeline Review, H1 2016 - New Report Available

Further, patient-derived bacteria and cells can be co-cultured in the presence of various antibiotics to determine whether antibiotic treatment blocks the cytotoxic activity of the isolate.

Phenotypic analysis of bacterial virulence using electric cell-substrate impedance sensing

Native PAGE of the chromatographic fractions from the last column chromatography showed only one band, indicating that the cytotoxic factor was electrophoretically purified.

Cytotoxic factor secreted by Escherichia coli associated with sepsis facilitates transcytosis through human umbilical vein endothelial cell monolayers

We are focusing on Disorazol Z," Sachse explained, "because it is an ideal compound for the formation of cytotoxic conjugates with peptides, proteins and antibodies to selectively target cancer cells.

Aeterna provides update on Zoptrex

8220;It also should help CMOs make strategic investment decisions when it comes to producing cytotoxic injectable drugs.

Pharma Industry's Capacity to Produce Cytotoxic Injectable Drugs Constricts

Protective clothing must be worn by all personnel preparing cytotoxic drugs, cleaning cytotoxic preparation facilities, or cleaning cytotoxic spills.

Sterile Pharmacy compounding services in hospitals: Learning from the tragic lessons of the past occurred in developed countries

Results: Data on cytotoxic effects could be obtained from primary cultures in 18 of the 27 recruited patients.

Sensitivity of primary cultures of breast cancer cells to different iscador[R]-preparations

A 1996 study published in the Archives of Environmental Health found that the cytotoxic drug methotrexate was present in urine samples of nurses who'd been caring for chemotherapy patients.

Protection from toxic drugs: new cytotoxic drug guidelines minimise nurses' exposure to toxic cancer drugs

Procedures that govern the use of cytotoxic medications for oncology indications are also applicable when medications such as cyclophosphamide are used for non-oncology purposes.

A near miss involving cyclophosphamide

Cytotoxic agents help to kill cancer cells--or stop them from multiplying--making them applicable in almost every cancer type.

Cytotoxic therapies to feel the sting of generics: cytotoxic therapy, or chemotherapy as it is commonly known, has been the cornerstone of cancer treatment for many years and involves the use of drugs that are toxic to all cells--including those that are perfectly healthy. While relatively effective, this leads to the unpleasant side-effects commonly associated with cytotoxic treatment, such as vomiting, nausea, alopecia and fatigue