cytotactin

cytotactin

A term that was widely used in the biomedical literature from the mid-1980s to mi-1990s for an extracellular matrix protein and cell substrate adhesion molecule, which is now known as tenascin cytotaxin or, preferably, as tenascin C.
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The selected genes include four encoding signaling proteins (FGFR3 encoding fibroblast growth factor receptor 3, EPHB2 encoding ephrin type-B receptor 2, GREM1 encoding gremlin 1, and IGFBP2 encoding insulin-like growth factor binding protein 2), two extracellular matrix genes (COL3A1 encoding collagen, type III, alpha 1, and TNC encoding cytotactin or tenascin-C), and two metabolic genes (ACBD7 encoding acyl-CoA-binding domain containing 7 and SCD encoding stearoyl-CoA desaturase).
Tenascin C (or TN-C with C for cytotactin) is a secreted extracellular matrix glycoprotein that is part of a family of three homologs along with Tenascin R and Tenascin X.
Molecular forms, binding functions, and developmental expression patterns of cytotactin and cytotactin-binding proteoglycan, an interactive pair of extracellular matrix molecules.