cytosol


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cytosol

 [si´to-sol]
the liquid medium of the cytoplasm, e.g., cytoplasm minus organelles and nonmembranous insoluble components. adj., adj cytosol´ic.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

cy·to·sol

(sī'tō-sol),
Fluid components of the cytoplasm exclusive of mitochondria, the endoplasmic reticulum, and other membranous and particulate components.
[cyto- + "sol," abbrev. of soluble]
Farlex Partner Medical Dictionary © Farlex 2012

cytosol

(sī′tə-sôl′, -sŏl′)
n.
The fluid component of cytoplasm, excluding the organelles and insoluble components such as cytoskeletal protein filaments.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

cytoplasm

The aqueous gel-like cell content of a living cell, which is located outside the nucleus and inside the plasma membrane, exclusive of the nucleus, organelles, ribosomes, Golgi apparatus, cytoskeleton, aggregates of storage compounds and other inclusions.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

cy·to·sol

(sī'tō-sol)
Cytoplasm exclusive of the mitochondria, endoplasmic reticulum, and other membranous components.
[cyto- + "sol," abbrev. of soluble]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

cytosol

The cell contents situated between the cell membrane and the nucleus, less the endoplasmic reticulum, the mitochondria and the other structured organelles.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

cytosol

the non-viscous, soluble portion of the cytoplasm including dissolved solutes but excluding any particulate matter. In the amoeba, cytosol forms the inner part of the organism, surrounded by cytogel which is more viscous.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
References in periodicals archive ?
Here, we demonstrated that one of the two isoforms of NDPK-like protein, i.e., DYNAMO2, is localized in the cytosol. Its expression is elevated during the S-M phase and well correlated with the dynamics of the global GTP level that is temporally elevated during the S-M phase.
The LIG_SH2_STAT5 motifs matched with amino acid residues YTER (296-299), a functional residue of STAT5 Src Homology 2 (SH2) domain binding motif in the cytosol. The LIG_CYCLIN_1 motifs in lined with amino acid residues amino acid residues RDLKV (323-327), which is a substrate recognition site that act together with cyclin and increases phosphorylation of cyclin/cdk complexes.
First, laser irradiation triggered doxorubicin release into the cytosol, which provides more free doxorubicin to elicit its pharmacological activity.
In the endosome-to-cytosol pathway, antigen degradation occurring in the proteasomes indicates that antigens internalized in endosomes need to be transported from the compartment to the cytosol [12].
Entry of lethal doses of abrin, ricin and modeccin into the cytosol of HeLa cells.
Other regulators such as thioredoxin-interacting proteins, activated by the increase in reactive oxygen species in cytosol, are thought to have minor effect on the formation of inflammasomes in M.tb infection [47].
In this study, we found that NF-[kappa]B was activated after 16 h of GD along with upregulation of P50 subunit and translocation of NF-[kappa]B (p65) from cytosol to nucleus.
The first study successfully identified GSTT1 as target antigen of LKC by testing positive sera with human liver cDNA expression library [6], the second used immunodiffusion assay exclusively with rat liver cytosol proteins [18], and the third one used two-dimensional IB assay performed with rat proteins to characterize both LKC and classical LKM-1 autoantibodies [7].
While the cells treated by DHB (2.5, 5 and 10 [micro]M) exhibiting green fluorescence indicated release of cytochrome c from mitochondria into cytosol. Western blot data also revealed significant upregulation of cytochrome c in the cytosolic fraction by DHB exposure (Fig.
Booth and colleagues say that one cause is the partial blocking of translocator protein sites--sites where ADP is moved into mitochondria for recycling and ATP is moved out of the mitochondria to the cytosol. The other cause is lack of substrate or essential cofactors--that is, nutrients.
There are numerous hypotheses that attempt to explain the aging process, considering complex physiological alterations in organisms, including: mitochondrial changes, accumulation of aberrant proteins in the cytosol, chemical damage to macromolecules, and somatic mutations.
Cytosol fractions were collected as described above for cytosolic cytochrome C measurement.