cytoskeleton


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cytoskeleton

 [si″to-skel´ĕ-ton]
a conspicuous internal reinforcement in the cytoplasm of a cell, consisting of tonofibrils, filaments of the terminal web, and other microfilaments. adj., adj cytoskel´etal.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

cy·to·skel·e·ton

(sī'tō-skel'ĕ-ton),
In cells, the microtubules and the filaments (thin, intermediate, and thick) that serve as supportive cytoplasmic elements to stiffen cells or to organize the location and movement of intracellular organelles.
Farlex Partner Medical Dictionary © Farlex 2012

cytoskeleton

(sī′tə-skĕl′ĭ-tn)
n.
The internal framework of a eukaryotic cell, composed of protein filaments that provide structural support and drive the movement of the cell and its internal components, typically divided into three categories (microfilaments, intermediate filaments, and microtubules) based on the diameter and composition of the filaments.

cy′to·skel′e·tal (-ĭ-tl) adj.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

cy·to·skel·e·ton

(sī'tō-skel'ĕ-tŏn)
The tonofilaments, keratin, desmin, neurofilaments, or other intermediate filaments serving as supportive cytoplasmic elements to stiffen cells or to organize intracellular organelles.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

cytoskeleton

A complex network of ACTIN filaments within the nucleated cell. Unlike the bony skeleton in vertebrates, this skeleton has contractile properties and can alter the shape, size and even movement, of the cell. The cytoskeleton is also concerned with the adhesion of adjacent cells.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

cytoskeleton

a network of MICROTUBULES and MICROFILAMENTS in the cytoplasm of cells which is thought to give the cell its characteristic shape. The network enables the movement of specific organelles within the cytoplasm (as in vesicles produced by the GOLGI APPARATUS), and the production of general CYTOPLASMIC STREAMING.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

cy·to·skel·e·ton

(sī'tō-skel'ĕ-tŏn)
The tonofilaments, keratin, desmin, neurofilaments, or other intermediate filaments serving as supportive cytoplasmic elements to stiffen cells or to organize intracellular organelles.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
The main findings of the present study include the following: (1) AGEs significantly induced hypertrophy and apoptosis and upregulated PFN-1 expression in H9c2 cells, concomitantly with F-actin redistribution and increased formation of F-actin as well as RAGE, RhoA, and ROCK2 protein expression; (2) knockdown PFN-1 expression ameliorated AGEs-induced cardiomyocytes hypertrophy and apoptosis; (3) blockade of ROS production, ROCK activation, or treatment with an actin depolymerizer also remarkably improved AGEs-induced myocardial injury, which is in line with down-regulated expression of PFN-1 and improved actin cytoskeleton alteration.
Assessing the Molecular Basis of Diphenyl Ditelluride Toxicity on the Cytoskeleton of Neural Cells
This rearrangement of organelles could be mediated through the dynamic filaments of cytoskeleton contraction towards the periphery in close proximity of cell membrane during M-phase and relaxation would bring back post-mitotically to the normal setting of organelles in daughter cells.
The cytoskeleton is a highly dynamic web composed of different molecules including actin, tubulin, and vimentin, whose role is dependent on the context and structures generated in each condition, but it also relies on the cell type.
Degranulation or exocytosis, cellular processes based on membrane dynamics, is also tightly associated with actin cytoskeleton [6].
The cell adherence on the surface of a coverslip was evaluated by measuring the distribution of cytoskeleton F actin in cryopreserved MSCs using phalloidin Alexa Fluor 488 staining.
As the effector of Rho GTPase, PAK4 controls the cytoskeleton primarily through the regulation of polymerized actin structures, particularly the formation of filopodia and lamellipodia, but can also act upon microtubule organization [9].
Enhanced UV-B radiation exerts strong impacts on plant growth and development, such as degradation of photosynthetic systems, alteration of secondary metabolism, modification of cell morphology, and impairment of the plant cytoskeleton (Xiong and Day, 2001; Hollosy, 2002; Gao et al., 2003; Zaets et al., 2006).
Conclusion: Using comparative proteomics, we identified eight differentially expressed proteins (including four cytoskeleton proteins and three proteins related to apoptosis) in the USL that may be involved in apoptosis associated with the tissue effects in POP pathophysiology.
Caption: A new microscopy technique gives scientists a better look at how an embryonic mouse cell's internal scaffolding, or cytoskeleton, changes overtime.
Anisina has been designed to inhibit a protein known as Tpm3.1, a structural protein and is a core component of the skeleton, or cytoskeleton of a cancer cell, concluded the company.