Common morphologic features of viral infection include
cytomegaly, syncytia formation, and intracytoplasmic and/or intranuclear inclusions.
Some of the less severe endpoints reported include "mild lesions" or "
cytomegaly" in an organ and "mild irritation," whereas some of the more severe endpoints include "atrophy" of the testes, "hemorrhage," or even "increased mortality." In all cases, the calculated [HD.sub.M]: refers to an estimated human dose at which a 1% incidence occurs, but clearly a 1% incidence of "mild irritation" has a very different severity than a 1% incidence of "increased mortality." This lack of standardization of endpoint severity also occurs with traditional RfDs but is less transparent.
One-fourth to one-third cases of PMD is associated with Beckwith-Wiedeman syndrome (10) (macrosomia, hemihyperplasia, visceromegaly, omphalocele, macroglossia, renal anomalies and adrenal
cytomegaly).
bacterial infections, infectious mononucleosis,
cytomegaly) and non infectious diseases (e.g.
Adverse events were hematotoxicity and grade 3/4
cytomegaly virus (CMV) infection (16%); however, the response duration following alemtuzumab is usually limited, making the search for effective first-line consolidation mandatory.
Infections Pancreatitis accompanying viral infections (mumps, hepatitis B,
cytomegaly, varicella zoster, herpes simplex, echo and coxsackie virus) is usually mild and self-limited.
(13-15) Examination of villi may reveal the characteristic
cytomegaly with intranuclear and intracytoplasmic inclusions (Figure 1, A and B).
Extreme
cytomegaly of the adrenal fetal cortex, omphalocele, hyperplasia of the kidneys and pancreas and leydig cell hyperplasia-another syndrome?
p Renal
cytomegaly. q Nest- like infolds of the nasal respiratory epithelium.
* HIV/AIDS, hepatitis,
cytomegaly (CMV), the Epstein-Barr (EBV) virus and other viral diseases typical for Africa are diagnosed, treated and monitored with blood.
Cytologic analysis of esophageal brushings reveals cells with
cytomegaly and pleomorphic, hyperchromatic nuclei with irregular chromatin patterns.