cytomegaly

cytomegaly

 [si″to-meg´ah-le]
abnormal enlargement of a cell or group of cells.
adrenocortical cytomegaly abnormal enlargement of cells in the outer layer of the adrenal cortex.
Cytology A general term for markedly enlarged cells seen on cervical smears which may be mono-, bi- or multinucleated; the nuclei may be dyskeratotic
Pathology A nonspecific term for a cell with abundant clear cytoplasm, which may be benign or malignant and may be of any embryologic origin and may contain any histologically clear material
Examples Carcinoid cells, ependymal cells (myxopapillary ependymoma, hepatocytes), ballooning degeneration, histiocytes storing glycosaminoglycans and mucopoly-saccharides, neurons (Farber’s disease, lipogranulomatosis, mannosidosis) and pigmented cells either benign (balloon cell nevus) or malignant (balloon cell melanoma)
References in periodicals archive ?
Common morphologic features of viral infection include cytomegaly, syncytia formation, and intracytoplasmic and/or intranuclear inclusions.
Some of the less severe endpoints reported include "mild lesions" or "cytomegaly" in an organ and "mild irritation," whereas some of the more severe endpoints include "atrophy" of the testes, "hemorrhage," or even "increased mortality." In all cases, the calculated [HD.sub.M]: refers to an estimated human dose at which a 1% incidence occurs, but clearly a 1% incidence of "mild irritation" has a very different severity than a 1% incidence of "increased mortality." This lack of standardization of endpoint severity also occurs with traditional RfDs but is less transparent.
One-fourth to one-third cases of PMD is associated with Beckwith-Wiedeman syndrome (10) (macrosomia, hemihyperplasia, visceromegaly, omphalocele, macroglossia, renal anomalies and adrenal cytomegaly).
bacterial infections, infectious mononucleosis, cytomegaly) and non infectious diseases (e.g.
Adverse events were hematotoxicity and grade 3/4 cytomegaly virus (CMV) infection (16%); however, the response duration following alemtuzumab is usually limited, making the search for effective first-line consolidation mandatory.
Infections Pancreatitis accompanying viral infections (mumps, hepatitis B, cytomegaly, varicella zoster, herpes simplex, echo and coxsackie virus) is usually mild and self-limited.
(13-15) Examination of villi may reveal the characteristic cytomegaly with intranuclear and intracytoplasmic inclusions (Figure 1, A and B).
Extreme cytomegaly of the adrenal fetal cortex, omphalocele, hyperplasia of the kidneys and pancreas and leydig cell hyperplasia-another syndrome?
p Renal cytomegaly. q Nest- like infolds of the nasal respiratory epithelium.
* HIV/AIDS, hepatitis, cytomegaly (CMV), the Epstein-Barr (EBV) virus and other viral diseases typical for Africa are diagnosed, treated and monitored with blood.
Cytologic analysis of esophageal brushings reveals cells with cytomegaly and pleomorphic, hyperchromatic nuclei with irregular chromatin patterns.