cytomegalovirus disease


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Related to cytomegalovirus disease: CMV

cytomegalovirus

 (CMV) [si″to-meg´ah-lo-vi″rus]
any of a subfamily of host-specific herpesviruses infecting humans, monkeys, and rodents, producing unique large cells with inclusion bodies. Opportunistic infection with this virus is common in immunocompromised individuals, causing clinical illnesses such as cytomegalovirus retinitis, pneumonia, esophagitis, colitis, adrenalitis, and hepatitis. It can also cause cytomegalic inclusion disease, a variety of gastrointestinal infections, and encephalitis. Most infections are mild in immunocompetent persons, but it has been associated with a syndrome called cytomegalovirus mononucleosis.
cytomegalovirus disease cytomegalic inclusion disease.

cy·to·meg·a·lic in·clu·sion dis·ease

caused by cytomegalovirus, a member of the Herpesviridae family; the presence of inclusion bodies within the cytoplasm and nuclei of enlarged cells of various organs of newborn infants dying with jaundice, hepatomegaly, splenomegaly, purpura, thrombocytopenia, and fever; the condition also occurs, at all ages, as a complication of other diseases in which immune mechanisms are severely depressed, and has been found incidentally in salivary gland epithelium, apparently as a localized or mild infection (salivary gland virus disease).
References in periodicals archive ?
Matas, "Cytomegalovirus disease recurrence after ganciclovir treatment in kidney and kidney-pancreas transplant recipients," Transplantation, vol.
Bethge et al., "Adoptive transfer of pp65-specific T cells for the treatment of chemorefractory cytomegalovirus disease or reactivation after haploidentical and matched unrelated stem cell transplantation," Blood, vol.
Antigenemia for cytomegalovirus in renal transplantation: choosing a cutoff for the diagnosis criteria in cytomegalovirus disease. Transplant Proc 2005; 37: 2781-3.
(3,4) The high burden of HIV disease and the increasing scale-up of HAART provision in South Africa (with patients often initiating treatment at low CD4 counts) suggest that cytomegalovirus disease, whether ocular or systemic, will have a huge impact on HIV-related morbidity and mortality.
Use of molecular assays in diagnosis and monitoring of cytomegalovirus disease following renal transplantation.
Evaluation of ganciclovir for cytomegalovirus disease. Drug Intell Clin Pharm 1989; 23(1):5-12.
Cytomegalovirus disease is a potentially life-threatening complication for immunosuppressed patients.
Razonable, "Epidemiology of cytomegalovirus disease in solid organ and hematopoietic stem cell transplant recipients," American Journal of Health-System Pharmacy, vol.
Preemptive treatment for cytomegalovirus viremia to prevent cytomegalovirus disease in solid organ transplant recipients.
oral ganciclovir for prevention of cytomegalovirus disease in solid organ transplant recipients," American Journal of Transplantation, vol.
Razonable, "Relationship between Toll-like receptor 2 polymorphism and cytomegalovirus disease after liver transplantation," Clinical Infectious Diseases, vol.
True (A) or false (B)--click on the correct answer: Gastro-intestinal cytomegalovirus disease in humans manifests only as proctitis.

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