Data from large randomized trials suggest
cytologic screening is slightly less sensitive than hrHPV testing in detecting high-grade (grade 2 or 3) cervical intraepithelial neoplasia (CIN).
Cytologic screening for the detection of cancer in the uterine cervix--A survey in Patna (India).
Some experts recommend anal
cytologic screening or high-resolution anoscopy for HIV-positive men and women, but it's worth noting that strategy hasn't been incorporated into any national practice guidelines.
A 4-step discordance was considered a
cytologic screening failure.
Acetic acid visualization of the cervix: an alternative to
cytologic screening. Obstet Gynecol 1996;88:383-6.
Whether
cytologic screening is efficacious in preventing anal cancer remains unproven (though probable), while cytology screening has proved valuable in preventing cervical cancer (though not in a randomized trial).
Digital anal-rectal examination and anal
cytologic screening followed by annual screening is recommended in the following women:
Castle and his colleagues analyzed data from a Portland, Ore., cohort of 19,512 women who underwent routine
cytologic screening when they were aged 16-94 years at baseline in 1989-1990.
Automated screening instruments have improved the sensitivity of
cytologic screening. Computer-assisted automated imaging screens for dark, hyperchromatic cells which are reviewed by CTs ensure the worrisome areas on each slide are examined so further diagnostic information can be provided.
These data support the need for studies of anal
cytologic screening of HIV-positive women.
For HPV or
cytologic screening, the nurse-midwives collected cervical cells for testing; women received results within two weeks, and those who tested positive were given appointments for colposcopy, biopsy and treatment.
The availability of a non
cytologic screening method not requiring a vaginal speculum examination may reduce underscreening in women who have access to health care.
