Centrosomes enhance the fidelity of cytokinesis
in vertebrates and are required for cell cycle progression.
In the mechanism studies, although initially the 4 small molecules were chosen based on their profound effect on cytokinesis
, they have also been proved playing important roles in cell cycle regulation [9, 21-25].
Aurora B kinase activity is essential for proper cytokinesis
(Adams et al., 2001; Echard et al., 2004; Eggert et al., 2004; Smurnyy et al., 2010) and, at onset of anaphase, the CPC complex relocalizes to the spindle midzone (Adams et al., 2000), an area comprised of stable, overlapping microtubules (MTs).
in microsporocyte meiosis is of the simultaneous type, and the micropore tetrads are tetrahedral.
Based on this phenomenon, cytokinesis
, the process of dividing the cytoplasm and the cell membrane, may follow a short time after mitosis, but not immediately.
Within the cell cycle set of genes, 16 genes were associated with various parts of the cell cycle including cytokinesis
, centromere formation, and microtubule formation.
In the all tetrads, the cytokinesis
was done as simultaneous type (Fig.
The data for the micronucleus test with cytokinesis
block and nuclear division index are reported in Table 3.
The cultures were incubated at 37 [degrees]C for 72 hours, and 44 hours after the initiation of cultures, cytochalasin-B (Sigma) at a concentration of 6mg/mL was added to arrest cytokinesis
. MN slides were stained with 10% Giemsa in phosphate buffer.
The members of the BTB protein gene family are functionally involved in a variety of biological events in eukaryotes, including developmental timing , oogenesis , organ formation , cell development [10,11], cell apoptosis [12,13], protein degradation [14-17], cytokinesis
[18,19], and tumorigenesis [20, 21].
During mitosis it localizes at the spindle poles to be inactivated and degraded before cytokinesis
, as above mentioned [19, 22].
The study shows RhoA is necessary for proper regulation of a cellular process called cytokinesis
during the final stage of cell division in hematopoietic progenitor cells, which produce specific types of blood cells.