cytokine storm


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A potentially fatal hyperrelease of inflammatory mediators in response to stimulation of T cells and macrophages by pathogens and immune insults
Triggers Graft versus host disease, adult respiratory distress syndrome, sepsis, avian influenza, and systemic inflammatory response syndrome

cytokine storm

The massive release of interleukins, tumor necrosis factor alpha, and other circulating mediators of inflammation during critical illness. These agents may trigger bleeding, clotting, internal organ injury, or shock.
See also: storm
References in periodicals archive ?
Cytokine storms are believed to be the primary cause of death in young and otherwise healthy people who are infected with influenza, particularly pandemic flu strains.
ProStorm[TM] is designed specifically to indicate when a cytokine storm first infusion reaction may be a risk for a drug.
Inhibiting virus multiplication after cytokine storm has set in does not seem to prevent viral pneumonia or ARDS.
Further studies will validate the beneficial effect of the anti-inflammatory response for temporizing the cytokine storm seen in influenza (H5N1).
Cytokine storms can result in autoimmune reactions, tissue damage, or septic shock.
ImmunoSIGNAL([TM]) Cytokine Storm Cellular Assay is a unique proprietary in vitro assay that evaluates biologics for their potential to induce cytokine storm.
The biggest cytokine storms, though, seem to come from the patients with the most advanced cancers.
A cytokine storm is a dysfunctional innate immune response involving unchecked production of pro-inflammatory mediators.
CytoSorb(R) has CE Mark regulatory approval, and is clinically proven to control cytokine storm in critically-ill patients by reducing key cytokines in blood by 30-50%.
ImmunoSIGNAL Cytokine Storm Cellular Assay is a unique proprietary in vitro assay that evaluates biologics for their potential to induce cytokine storm.
Research studies and review articles published in the journal Viral Immunology reveal that a cytokine storm occurs when the body's immune system over-reacts to an intruder, such as a virus, by producing high levels of cytokines.
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