KRT20

(redirected from cytokeratin-20)

KRT20

A gene on chromosome 17q21.2 that encodes a type-I keratin, an intermediate filament protein that is a major cellular protein of mature enterocytes and goblet cells, and is specifically expressed in gastric and intestinal mucosa.
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In tumour tissue, immunoreaction was observed only by vimentin, but no expressions were observed with pankeratin, epithelial membrane antigen (EMA), carcinoembryonic antigen (CEA), cytokeratin-7, cytokeratin-20, leukocyte common antigen (LCA), smooth muscle actin (SMA), desmin, Myo-D1, chromogranin-A, synaptophysin, S100 protein, HMB45, CD68, CD30, CD34, CD31, factor VIII, alpha feto protein (AFP), beta human chorionic gonadotropin ((beta) hCG), placental alkaline phosphatase (PLAP), and Neu-N.