KRT7

(redirected from cytokeratin 7)

KRT7

A gene on chromosome 12q13.13 that encodes a type-II cytokeratin specifically expressed in the simple epithelia of internal organs, glands, ducts and blood vessels.
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Murine anti-human cytokeratin 7, Clone ov-tl 12/30, Ready for use; Monocl.
Immunohistochemistry showed cytokeratin 5/6 (+) (c, 10x), P63 (+) (d, 10x), cytokeratin 7 (-), TTF-1 (-) and Ki67 (50%).
2), epithelial membrane antigen (EMA), cytokeratin 7 (CK7), carbonic anhydrase IX (CA-IX), CD117, melanoma antigen recognized by T cells 1 (Mart-1), microphthalmia-associated transcription factor (MiTF) and Melan-A.
The immunohistochemical stains performed were Neuron Specific Enolase (NSE) (Dako,1:400), Chromogranin A (Dako, 1:5000), CD56 (NovoCas- tra,1:50), Neurofilament (Dako,1:400), S-100 (Dako, 1:1000), Synaptophysin (Biogenex, 1:400), Vimentin (Vim 3B4 Dako, 1:100), CD 99 (mic-2 12E7 Dako, Pre-diluted), Cytokeratin (clone AE1/AE3 Dako 1:50), Epithelial Membrane Antigen (EMA) (E29, Dako, 1:50), Cytokeratin 7 (OV-TL 12/30, Dako, 1:100), CD117 (c-kit - Dako, 1:100), Desmin (D33, Dako, 1:150), Cytokeratin CAM 5.
The immunostain for cytokeratin 7 was positive in the majority of the tumour cells (Fig.
Immunohistochemical stains revealed the tumor cells to be strongly and diffusely positive for cytokeratin 7.
Suprapubic region, Paget's cells, cytokeratin 7, carcinoembryonic antigen.
The mediastinal tumor samples taken from our patient stained positively for vimentin, muscle-specific actin, and desmin and were negative for cytokeratin AE 1/3, cytokeratin 7, cytokeratin 20, epithelial membrane antigen (EMA), calretinin, S100 protein, melanoma antibody (HMB45), and leukocyte common antigen.
The use of cytokeratin 7 and EMA in differentiating ovarian yolk sac tumors from endometrioid and clear cell carcinomas.
The immunohistochemical studies revealed tumor cell positivity for cytokeratin 19, carcinoembryonic antigen (partial positive), villin, caudal-related homeodomain transcription-2, and Ki67 50%, but studies were negative for TTF-1, cytokeratin 7, cytokeratin 20, and NapsinA.
Immunohistochemically, the tumour cells stained positive for cytokeratin (AE1/AE3), cytokeratin 7, and c-kit (weak staining) and negative for vimentin and CD10 (Fig.
Metastatic breast carcinomas are usually positive for gross cystic disease fluid protein-15 (GCDFP-15), cytokeratin 7, carcinoembryonic antigen, estrogen receptor, and progesterone receptors, and negative for cytokeratin 20.