(ii) Unexpectedly, increased cytogenic
abnormalities in number and severity were recorded in cells, cultured with antioxidant supplementation.
The effect of cement dust exposure on hematological and cytogenic
studies of cement workers.
No specific translocations or genetic abnormalities in humans have been identified to cause OS; (14,50,54) However, approximately 70% of OS tumor cells display the contribution of some genetic variation, which leads to cytogenic
effects of cyanazine and metolachlor on human lymphocytes exposed in vitro.
While limited in number, studies performed to assess the effect of methylation on chromosome segregation have consistently shown an increase in the frequency of cytogenic
abnormalities associated with perturbations in the methylation status of chromosomes .
The MGMT enzyme removes mutagenic and cytogenic
adducts from O6-guanine in DNA, via a one-step methyl transfer reaction (Lindahl et al., 1988).
(5) Histopathological analysis (and sometimes even special immunohistochemical staining and cytogenic
analysis) can be used to make a definitive diagnosis.
analyses were performed, investigating specifically the role of a primitive tissue known as a[euro]oeundifferentiated gonadal tissue.
Other than pleuropulmonary blastoma family tumor and dysplasia syndrome, a rare syndrome related to germline mutation of DICER1 gene, most intraocular medulloepitheliomas occur sporadically and are not associated with congenital malformation or cytogenic
21 November 2011 - Celgene International Sarl, part of US Celgene Corp (NASDAQ:CELG), said today that the Swiss agency for Therapeutic Products (Swissmedic) had cleared REVLIMID (lenalidomide) to treat patients with transfusion-dependent anemia due to low-or intermediate-1-risk myelodysplastic syndromes (MDS) related to a deletion 5q cytogenic
abnormality with or without additional cytogenic
Chronic long-term nitrate therapy: Possible cytogenic
effect in humans?
study showed 46XY/46XX mosaic chromosomal pattern.