cytogenetics

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cytogenetics

 [si″to-jĕ-net´iks]
that branch of genetics devoted to the cellular constituents concerned in heredity, i.e., the chromosomes.
clinical cytogenetics the branch of cytogenetics concerned with relations between chromosomal abnormalities and pathologic conditions.

cy·to·ge·net·ics

(sī'tō-jĕ-net'iks),
The branch of genetics concerned with the structure and function of the cell, especially the chromosomes.

Cytogenetics arose as a fusion of 19th-century cytology and 20th-century genetics, which came into being in 1903 with the articulation of the chromosome theory of inheritance. The developing field concerned itself with detailing the behavior of chromosomes and their functional subunits, the genes, during reproduction, and with relating that behavior statistically to characteristics of the resulting cells or animals. Modern molecular cytogenetics involves the microscopic study of chromosomes that have been fixed in mitosis and stained with various agents to delineate characteristic bands. DNA probes can be applied to locate specific gene sequences. Karyotyping is the arrangement of photographs of stained chromosomes in a standard format. Cytogenetic techniques are used to test for inborn errors of metabolism and genomic aberrations such as Down syndrome and to determine sex in cases where anatomy is inconclusive.

cytogenetics

(sī′tō-jə-nĕt′ĭks)
n. (used with a sing. verb)
The branch of genetics that deals with the cellular components, particularly chromosomes, that are associated with heredity.

cy′to·ge·net′ic, cy′to·ge·net′i·cal adj.
cy′to·ge·net′i·cal·ly adv.
cy′to·ge·net′i·cist (-sĭst) n.

cy·to·ge·net·ics

(sī'tō-jĕ-net'iks)
The branch of genetics concerned with the structure and function of the cell, especially the chromosomes. Modern molecular cytogenetics involves the microscopic study of chromosomes that have been arranged as karyotypes. Individuals can be classified according to characteristic banding patterns that appear when the karyotypes are exposed to some dyes. In addition, DNA probes may be applied to locate specific gene sequences. Cytogenetic techniques are used to test for inborn errors of metabolism, for disorders such as Down syndrome, and to determine sex in cases where anatomy is inconclusive.

cytogenetics

the study of the inheritance of cells and their chromosomes. Cytogenetic analysis of foetal cells (see AMNIOCENTESIS and CYSTIC FIBROSIS) is used to assess potential risks to the baby.
References in periodicals archive ?
"One cell is going to get more than the other does," says cytogeneticist Jerome L.
The GenASIs platforms offer a comprehensive solution ensuring reliability and quality results every time, while allowing cytogeneticists, pathologists and technologists to focus on the clinical rather than the technical components.
GenASIs enables automated pathology tissue analysis for primary diagnostics, creating reproducible and reliable results as well as a comprehensive solution ensuring reliability and quality results, while allowing cytogeneticists, pathologists and technologists to focus on the clinical rather than the technical components.
Paraphrasing and altering the famous remark of Muller (1922) we may ask: "Must we evolutionists become cell physiologists, electron microscopists and molecular biologists as well as ecologists, cytogeneticists and population geneticists?
During the Sino-Japanese War and subsequent World War II, the small group of plant cytogeneticists in West China consisting of H.W.
With superior imaging and analysis capabilities, ASI provides state of the art diagnostic aids, offering cytogeneticists and pathologists accurate analysis.
National Down syndrome cytogenetic register and association of clinical cytogeneticists. J Med Genet 1996;33:387-94.
9.4: Expert Consensus Opinion.--A pathologist should participate in the interpretation of ALK FISH slides, either by performing the analysis directly or by reviewing the interpretations of cytogeneticists or technologists with specialized training in solid tumor FISH analysis.
With its superior imaging and analysis capabilities, ASI provides state of the art diagnostic aids, offering cytogeneticists and pathologists accurate genetic and pathology analysis.