2013), the direct cytocidal
effects of Cordyceps are not significant (Zhou et al.
On the other hand, T24 cells needed more than 30 minutes of exposure to sterile water to have a cytocidal
The methanol extract from calyces showed significant selective activity against a leukemia line (K-562), with concentration-dependent, cytotoxic and cytocidal
Thus, analysis of the expression of the genes encoding these 2 proteins may reveal an association with the cytostatic and cytocidal
effects of drugs, similar to the bacteriostatic and bacteriocidal effects of antibiotics.
Additionally, the antibodies tested were cytostatic in vitro but cytocidal
in vivo, indicating that the host environment may also play an important part in defining anti-tumour activity.
cell culture tests for the presence of certain cytocidal
viruses (by inoculation of and blind passage in Vero, MRC-5, HeLa, RK, and A9 cells with observations for cytopathology and tests for hemadsorption and hemagglutination at the end of the culture period), and animal inoculation tests for certain viruses (suckling and adult mice, guinea pigs, and embryonated hen eggs).
and potential antitumor properties of a class of quinoid compounds, initiators of dormant state in spores of Agaricus bisporus.
We have previously noted that expression by neuroblastoma cells of the p75NTR enhances the mitochondrial oxidative activity and cytocidal
efficacy of fenretinide in vitro [5,10].
For instance, Artepilin C (3,5-diprenyl-4-hydroxycinnamic acid) exhibits potent cytocidal
effects and induces marked levels of apoptosis which may be partially associated with enhanced Fas receptor expression and loss of the mitochondrial membrane potential in human leukemia cell lines in vitro (Kimoto et al.
Coronavirus infections can be cytocidal
for the cells; or, in some cases, persistent infection can result (17).
and cytostatic chemosensitivity test by measuring total amount of mRNA.
IFN-[gamma] induces various pro-inflammatory cytokines and biochemical pathways including the expression of distinct enzymes such as GTP-cyclohydrolase I (GTP-CH1) and indoleamine 2,3-dioxygenase (IDO), as well as the formation of cytocidal
reactive oxygen species (ROS) by human monocytes/macrophages and other immune effector cells (Fig.