Surgical excision is demonstrated if the mass persists to adulthood or reaches 5 cm which can lead to risk of developing giant fibroadenoma or cystosarcoma
phyllodes (1, 2, 13).
Giant fibro-adenoma (cystosarcoma
phyllodes) in adolescent females-a clinicopathological study.
Phyllodes tumor is a rare biphasic neoplastic lesion of the breast composing of stromal and epithelial components.1 Its incidence is 0.3-1% of all the breast tumors.2 It was first described by the name cystosarcoma
phyllodes by Mullor which was labeled to the present name by WHO classification in 1982.3,4 It is divided into benign and malignant depending upon stromal and atypical cells.5 About 70-90% of tumors are benign.
To the Editor: Phyllodes tumors are rare fibroepithelial malignancies of the breast and account for <1% of all malignant breast tumors. It is difficult to distinguish from fibroadenomas, while malignant cystosarcoma
phyllodes can grow in size quickly and metastasize early. Gigantic cystosarcoma
phyllodes of the breast is very rare, thus limiting our understanding of the disease and influencing diagnostic and management outcomes.
Stromal sarcomas of the breast: a unified approach to connective tissue sarcomas other than cystosarcoma
Primary osteosarcoma of the breast is a rare and aggressive malignancy that should be differentiated from two other similar tumors: metaplastic carcinoma and cystosarcoma
But 1 case was misdiagnosed as malignancy and turned out to be benign cystosarcoma
phyllodes, a benign lesion.
Malignant phyllodes tumor, previously known as cystosarcoma
phyllodes or periductal stromal tumor, is a lobulated and well-demarcated solid tumor with homogeneous or heterogeneous echo-texture.
Differential diagnosis of juvenile gigantomastia includes fibroadenomas, cystosarcoma
phylloides, gravid hypertrophy of the breast, breast hypertrophy secondary to endocrine disorders, pseudogigantomastia associated with obesity, and malignant tumors such as lymphomas and sarcomas (11).
phyllodes arising synchronously in right breast and bilateral axillary ectopic breast tissue," Archives of Pathology and Laboratory Medicine, vol.
Cosgrove, "Osteogenic sarcoma of the breast arising in a cystosarcoma
phyllodes: a case report and review of the literature," Journal of Medical Case Reports, vol.
Jones, "Immunohistochemical profile of cystosarcoma
phyllodes of the breast: a study of 23 cases," Breast Journal, vol.