cystic


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cystic

 [sis´tik]
1. pertaining to or containing cysts.
2. pertaining to the urinary bladder or to the gallbladder.
cystic disease of breast fibrocystic disease of breast.
cystic fibrosis a hereditary disorder associated with widespread dysfunction of the exocrine glands, with accumulation of excessively thick and tenacious mucus and abnormal secretion of sweat and saliva; it is inherited as a recessive trait; both parents must be carriers. The cause is thought to be absence, insufficiency, or abnormality of some essential hormone or enzyme. Called also cystic fibrosis of the pancreas and mucoviscidosis.
Effects. The symptoms and severity vary widely. Although cystic fibrosis is congenital, it may not manifest itself significantly during the early weeks or months of life, or it may cause intestinal obstruction and perforation in the newborn. The chief cause of complications is the extremely thick mucus produced. Normal mucus bathes and protects internal surfaces, transports chemicals produced in one organ through intricate small ducts to another organ, and carries bacteria, dirt, and wastes to be eliminated from the body; thus it needs to flow easily. The mucus of cystic fibrosis, in contrast, is highly adhesive. Bacteria and other matter stick to it, and it in turn clogs the lungs and usually interferes with the flow of digestive enzymes from the pancreas to the small intestine.

In the lungs, the mucus blocks the bronchioles, creating breathing difficulties. Infection develops, thereby increasing obstruction of the air passages. Air becomes trapped in the lungs (emphysema), and scattered small areas eventually collapse (patchy atelectasis). Repeated infections follow, inflaming and damaging lung tissue and leading to chronic lung disease. The organism that produces infection in cystic fibrosis is almost always a staphylococcus, but other organisms may be present in more severe cases. About half of children with cystic fibrosis have lung-related symptoms.

When mucus prevents the pancreatic enzymes from reaching the duodenum (as in about 80 per cent of cystic fibrosis patients), digestion is hindered. Fats especially are poorly digested and absorbed. The child may have a voracious appetite, yet fail to grow normally or gain weight. There may be marked signs of malnutrition. The outstanding symptom associated with pancreatic enzyme deficiency is frequent bulky, fatty, and foul-smelling feces.

Between 5 and 10 per cent of cystic fibrosis babies are born with intestines obstructed by puttylike intestinal secretions (meconium ileus) and die unless the condition is diagnosed promptly and relieved by surgery within the first few days of life. Such relief does not protect the child against the other manifestations of cystic fibrosis, although these may not appear until later.

Because cysts and scar tissue on the pancreas were observed during autopsy when the disease was first being differentiated from other conditions, it was given the name cystic fibrosis of the pancreas. Although this term describes a secondary rather than primary characteristic, it has been retained.
Diagnosis. Sweat in cystic fibrosis is excessively salty. Collapse of cystic fibrosis patients from salt loss during a heat wave led to recognition of the sweat abnormality. The sweat chloride test remains the cornerstone of diagnosis of cystic fibrosis. In children, a sweat chloride level above 60 mEq/l indicates cystic fibrosis. Newborn infants do not produce sufficient sweat for the test, but it has been noted that older babies “taste salty” when kissed. Supporting evidence can confirm the sweat test finding.
Treatment. Under careful supervision by the health care team, parents are taught the principles of home treatment of cystic fibrosis. The child may be required to sleep regularly in a plastic mist tent, into which a dense fog is pumped to help liquefy mucus and check infection. Aerosol therapy is generally prescribed. Extracts of animal pancreas taken with meals, which should be high in protein and low in fat, compensate for pancreatic deficiency. Physical therapy involving postural drainage together with “clapping” and “vibrating” aids in loosening the mucus so that it can be coughed up and expectorated.

It is estimated that in the United States cystic fibrosis occurs once in every few thousand births. Caucasians appear more subject to it than blacks, and among those of Asian descent it seems to be rare.
Patient Care. Maintenance of the child's nutritional status may be difficult because of his tendency to cough and vomit frequently during feedings, and also because of difficulty in breathing. Small amounts of food, given slowly and at frequent intervals, are best for infants as well as for small children with cystic fibrosis.

Skin care is important, especially for infants and toddlers who are not yet toilet trained. The stools are likely to be copious and extremely irritating to the skin. Frequent turning of the infant or bedridden child helps to prevent decubitus ulcers and lessens the danger of pneumonia, a constant threat to these children. Prevention of infection is a most important aspect of the care of these children because of their extreme vulnerability to disorders of the respiratory tract.

Education of the parents must include the dietary regimen; how to use the Croupette, a machine for aerosol therapy in the home; hygienic measures to prevent infections; and the importance of continuous medical follow-up and administration of medications prescribed for the child.
 Cystic fibrosis. The abnormal chloride transport associated with cystic fibrosis in a lack of sodium chloride in the secretions of all exocrine glands, especially the pancreas, intestine, and bronchi. Redrawn from Damjanov, 2000.
cystic kidney disease (cystic disease of kidney) see acquired cystic kidney disease and polycystic kidney disease.

cys·tic

(sis'tik),
1. Relating to the urinary bladder or gallbladder.
2. Relating to a cyst.
3. Containing cysts.

cystic

(sĭs′tĭk)
adj.
1. Of, relating to, or having characteristics of a cyst.
2. Having or containing cysts or a cyst.
3. Enclosed in a cyst.
4. Anatomy Of, relating to, or involving the gallbladder or urinary bladder.

cys·tic

(sis'tik)
1. Relating to the urinary bladder or gallbladder.
2. Relating to a cyst.
3. Containing cysts.

cystic

Adj
1. Pertaining to, or containing, a CYST or bladder.
2. Contained within a cyst of bladder.

Patient discussion about cystic

Q. Can cystic fibrosis patients have children? My boyfriend has cystic fibrosis, and currently he’s treated with many medications but usually healthy (other than pneumonia from hospitalization from time to time). I heard that men with cystic fibrosis can’t have children - is that true? Is there anything he can do about it?

A. WE ARE A HEALTHY COUPLE BUT MY WIFE NEVER GET PREGNANT IN 20 YEARS OF RELATIONSHIP.
I'M SO SORRY ABOUT MY ENGLISH, I'M LEARNING.

Q. Do women with cystic fibrosis have difficult pregnancy? My wife has cystic fibrosis, and after 3 year of marriage we decided we want a baby. I know that men with cystic fibrosis are usually infertile and can’t have children- is that the case also for women with cystic fibrosis? Is the pregnancy in women with cystic fibrosis more problematic? Is it dangerous?

A. Before you attempt a pregnancy, you should consult her doctor to make sure she can tolerate it, because very severe disease can make the pregnancy dangerous for her. If her disease isn’t so severe, usually there are no special problems.

Q. My daughter has a cystic mygroma. Has anyone else had this or know anyone who has, and how did you treat it? I really need some help on this issue, she has it in her neck and they say they shouldn't opperate because it may come back. I hope that someone out here can help me.

A. cystic hygroma is a benign lesion. therefore if surgery is not an option (the lesion is placed in a risky to operate area) they tend not to do so.. they use Sclerosing agents as Terrany suggested. include OK-432 , bleomycin, pure ethanol, bleomycin, sodium tetradecyl sulfate, and doxycycline.
ask your Doctors about them.

More discussions about cystic
References in periodicals archive ?
The Metro DC Chapter of the Cystic Fibrosis Foundation will host its 9th Annual CF Cycle for Life as part of one of the largest national events to raise funds and awareness for cystic fibrosis, a rare, genetic disease that progressively limits the ability to breathe and ultimately causes premature death.
The breakthrough involved a petri dish with 3D cell structures, or organoids, from cystic fibrosis patients.
Cystic fibrosis patients often suffer from severe, persistent secondary bacterial lung infections due to their underlying lung disease which results in an immune-compromised state.
Orkambi is licensed to treat cystic fibrosis in patients from two-year-olds to adults, who have a specific genetic mutation known as F508del.
Michael Stephen, Drexel University College of Medicine Cystic Fibrosis center director.
Twenty-six patients diagnosed with cystic fibrosis by the Department of Pediatric Chest Diseases were included in the study.
Patient underwent wide excision, where the intraoperative findings showed a superficial cystic swelling with few loculi over the muscle layer of the mylohyoid and the anterior belly of the digastric with few finger-like extensions between the muscle planes.
The youngster, from Prestwich, has now written to Theresa May urging her to support a campaign to allow people with cystic fibrosis access to new medicines.
The Cystic Fibrosis Trust claims Orkambi could treat around half the number of people with the condition in the UK, including up to 189 people in Wales who could benefit from the treatment now or in the future.
Effective from 1st January 2018, eligible people with cystic fibrosis who are taking Pulmozyme (dornase alfa), another CF medication, will be able to add reimbursed Bronchitol to their treatment regime.