cystathionine beta-synthase

(redirected from cysteine synthase)

cys·ta·thi·o·nine β-syn·thase

(sis'tă-thī'ō-nēn sin'thās),
An enzyme catalyzing the reversible hydrolysis of l-cystathionine to l-serine and l-homocysteine. A step in cysteine biosynthesis and in methionine catabolism. A deficiency of this enzyme leads to vascular thrombosis, dislocation of ocular lens, and abnormal development.
See also: cystathionine γ-synthase.
References in periodicals archive ?
halleri possess the enzyme "Cysteine synthase 1" under GO term response to Cd as species-specific term (Kawashima et al., 2004; Kim et al., 2011).
Heavy metal tolerance of transgenic tobacco plants over-expressing cysteine synthase. Biotechnology Letters.
Cysteine synthase can promote the use of sulfur, further converted into antioxidant substances of glutathione, and it's up-regulated expression can enhance the disease resistance of plants (Romero et al., 2015).
Upregulation of cysteine synthase and cystathionine [beta]-synthase contributes to Leishmania braziliensis survival under oxidative stress.
Nearly all of the proteins altered in significant amounts were identified as enzymes associated with important metabolic pathways, such as alcohol dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), Xaa-His dipeptidase, ornithine carbamoyltransferase, putative O-acetylserine lyase, enolase (2-phosphoglycerate dehydratase), fructose-bisphosphate aldolase, and cysteine synthase. Four of these enzymes including alcohol dehydrogenase, GAPDH, enolase, and fructose-bisphosphate aldolase, are involved in the glycolysis and gluconeogenesis pathways (Fig.
Sulfur assimilation in soybean: Molecular cloning and characterization of o-acetylserine (thiol) lyase (Cysteine synthase).
Molecular and biochemical analysis of serine acetyltransferase and cysteine synthase towards sulfur metabolism engineering.
Soybean OAS-TL contains the conserved PXXSVKDR motif that is characteristic of cysteine synthase. The lysine residue in this conserved motif has been shown to bind the co-factor pyridoxal 5'-phosphate.
Four rice genes encoding cysteine synthase: isolation and differential responses to sulfur, nitrogen and light.
Molecular cloning and bacterial expression of cDNA encoding plant cysteine synthase. Proc.
cDNA cloning and expression of cysteine synthase B localized in chloroplasts of Spinacea oleracea.
[O-acetylserine (thiol) lyase] Modulation of cysteine biosynthesis in chloroplast of transgenic tobacco overexpressing cysteine synthase. Plant Physiol.

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