cystathionine beta-synthase

(redirected from cystathionine b-synthase)

cys·ta·thi·o·nine β-syn·thase

(sis'tă-thī'ō-nēn sin'thās),
An enzyme catalyzing the reversible hydrolysis of l-cystathionine to l-serine and l-homocysteine. A step in cysteine biosynthesis and in methionine catabolism. A deficiency of this enzyme leads to vascular thrombosis, dislocation of ocular lens, and abnormal development.
See also: cystathionine γ-synthase.
References in periodicals archive ?
1,25-dihydroxyvitamin D3 influences cellular homocysteine levels in murine in pre-osteoblastic MC3T3-E1 cells by direct regulation of cystathionine b-synthase. J Bone Miner Res.
Cystathionine b-synthase Methionine synthase Methylenetetrahydrofolate reductase
Cystathionine B-synthase polymorphisms and hyperhomocysteinemia: an association study.
A yeast assay for functional detection of mutations in the human cystathionine b-synthase gene.
HT-CBS, heterozygotes for cystathionine b-synthase deficiency.