cyproterone acetate


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Related to cyproterone acetate: Androcur
An antiandrogenic progestin, which acts specifically on androgen receptors
Indications Prostate cancer, benign prostatic hyperplasia, priapism, hypersexuality—in particular sex offenders—hirsutism especially in male-to-female transgendered people, acne and hot flashes

cyproterone acetate

A male sex hormone antagonist drug used to treat hypersexuality and prostate gland enlargement. Brand names are Androcur and Cyprostat.
References in periodicals archive ?
Double-blind placebo crossover study of cyproterone acetate in the treatment of the paraphilias.
Comparison of cOCPs (having ethinyl estradiol 30 mcg/ desogestrel 150 mcg) plus spironolactone with cOCPs (containing ethinyl estradiol 35 mcg/ cyproterone acetate 2 mg) was done by Leelaphiwat et al and it showed improvement in mFG score from 4.27 +- 1.94 to 4.07 +- 1.91 in the combination group after 3 months of treatment18.
In the study by Somunkiran et al (5), AMH levels of 30 adult patients with PCOS were measured before and after 6 months of treatment with OC (35 mcg ethinyl estradiol+2 mg cyproterone acetate), with no significant changes detected; however, reduction in ovarian volume and follicle count were observed.
Efficacy of venlafaxine, medroxyprogesterone acetate, and cyproterone acetate for the treatment of vasomotor hot flushes in men taking gonadotropinreleasing hormone analogues for prostate cancer: A double-blind, randomised trial.
Ten studies evaluated minoxidil; four evaluated finasteride; two, cyproterone acetate; and two, flutamide.
Treatments for hirsutism range from the Pill - Dianette is a favourite - to anti-androgens such as cyproterone acetate, which block the effect of androgen on hair follicles.
Flutamide, is much less potent by weight and binding affinity than either spironolactone or cyproterone acetate, [14] but at the doses used, has usually been found to be more effective than either of them as an antiandrogen.
PRAC subsequently concluded that "the benefits of Diane 35 (cyproterone acetate 2 mg, ethinylestradiol 35 micrograms) and its generics outweigh the risks, provided that several measures are taken to minimise the risk of thromboembolism."
and a second review, under the simplified procedure (60 days) of the Diane 35 pill, and other medicines containing cyproterone acetate 2 mg, ethinylestradiol 35 mg.
Muscat: The Ministry of Health has banned the import, distribution and sale of an acne drug called Diane 35 (cyproterone acetate, 2 micrograms; ethinylestradiol, 35 micrograms), a statement from the Ministry of Health said.
Cyproterone acetate (Sigma-Aldrich) was diluted with 100% ethanol and used at a 10 uM concentration.

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