cyclosporin A


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Related to cyclosporin A: methotrexate, tacrolimus, Statins

cyclosporine

 [si″klo-spōr´in]
a cyclic peptide from an extract of soil fungi, an inhibitor of t cell function; used as an immunosuppressant to prevent and treat rejection in organ transplant recipients and to treat severe psoriasis and as a disease-modifying antirheumatic drug.

cyclosporin A

/cy·clo·spor·in A/ (-spor´in) cyclosporine.

cyclosporin A

References in periodicals archive ?
Topical cyclosporin A indications include among others, prevention of corneal graft rejection, ocular surface inflammatory diseases with an autoimmune component such as Sjoegren disease, vernal conjunctivitis, and peripheral ocular rheumatoid ulceration.
Microscale high-performance liquid chromatography-electrospray tandem mass spectrometry assay for cyclosporin A in blood.
CycloXome is Vestar's liposomal formulation of cyclosporin A, and has demonstrated promising ability in overcoming multiple drug resistance.
In the "Synthesis and Biological Evaluation of Novel Cyclosporin A Analogues: Potential Soft Drugs for the Treatment of Autoimmune Diseases" (Journal of Medicinal Chemistry) paper Enanta scientists discovered a highly efficient method to synthesize Cyclosporin A analogues targeted for the treatment of asthma, psoriasis, and inflammatory bowel disease.
He led the development, registration and approval of cyclosporin as well as six other major compounds.
The FDA has granted Orphan Drug designation to Maas BiolAB for cyclosporin as a treatment for ALS.