cycloserine


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Related to cycloserine: Ethionamide

cycloserine

 [si″klo-ser´ēn]
an antibiotic elaborated by Streptomyces orchidaceus or produced synthetically, used as a tuberculostatic and in the treatment of urinary tract infections.

cy·clo·ser·ine

(sī'klō-ser'ēn),
An antibiotic produced by strains of Streptomyces orchidaceus or S. garyphalus with a wide spectrum of antibacterial activity.
Synonym(s): orientomycin

cycloserine

(sī′klō-sĕr′ēn)
n.
An antibiotic effective against a wide range of bacteria, used especially in the treatment of tuberculosis and infections of the urinary tract.

cycloserine

Infectious disease A broad-spectrum antibiotic used for UTIs and TB Adverse effects CNS Sx, allergy, skin rash, ↑ LFTs

cy·clo·ser·ine

(sī'klō-ser'ēn)
An antibiotic produced by strains of Streptomyces orchidaceus or S. garyphalus with a wide spectrum of antibacterial activity.

cycloserine

A drug used to treat TUBERCULOSIS caused by organisms resistant to treatment by standard drugs such as rifampicin, isoniazid, ethambutol and streptomycin. The drug is on the WHO official list.

cy·clo·ser·ine

(sī'klō-ser'ēn)
An antibiotic produced by strains of Streptomyces orchidaceus or S. garyphalus with a wide spectrum of antibacterial activity.
References in periodicals archive ?
By typing cyclos," the CPOE brings up both the orders for cyclosporine level" and cycloserine level." The physician can then select the appropriate order.
Overall resistance to ofloxacin was highest (23%) followed by ethionamide (13%), PAS (7%), kanamycin (6%) and cycloserine (1%).
Despite the fact that there are several formulations of CS available in the market, surprisingly the authors could not find the formula of Cycloserine capsules in the literature, including patents.
Of these, 13 had termination of ethionamide, 4 of ofloxacin, and 1 each had kanamycin, ethambutol, pyrazinamide or cycloserine terminated.
Pharmacokinetics of cycloserine under fasting conditions and with high-fat meal, orange juice, and antacids.
Perfringens Agar OPSP uses a combination of sulphadiazine, oleandoymcin & polymyxin to achieve selectivity, whilst cycloserine is used with the TSC formulation.
Treatment of cutaneous M marinum infection consists of oral rifampin (600 mg daily) plus ethambutol (15 mg/kg/d), trimethaprim/sulfamethoxazole, minocycline, or doxycycline for at least 6 weeks.[10-12] Amikacin and kanamycin are also effective.[13] Alternative treatments include erythromycin, ciprofloxacin, or cycloserine.[11] Treatment with steriods will worsen the infection.[14] The organism is usually resistant to isoniazid and streptomycin.
We tested the strain for drug susceptibility to the first- and second-line drugs (streptomycin, isoniazid, rifampin, ethambutol, prothionamide, ofloxacin, kanamycin, capreomycin, and cycloserine).
The patient was started on antituberculosis therapy with isoniazid, rifabutin, pyrazinamide, ethambutol, and cycloserine. His antiretroviral therapy was modified to avoid drug interactions with antituberculosis regimen.
Other augmentation options include lithium, buspirone, and pindolol, as well as naturally occurring agents such as L-methylfolate, S-adenosylmethionine, creatine, omega-3 fatty acids, and cycloserine.
The RNTCP under PMDT recommends a standardized treatment regimen (STR) category four (CAT IV) regimen, comprising six drugs (kanamycin, levofloxacin, ethionamide, cycloserine, pyrazinamide, and ethambutol) during the 6-9 months of the intensive phase (IP) and four drugs (levofloxacin, ethionamide, cycloserine, and ethambutol) during the 18 months of the continuation phase (CP).