cyclodextrin


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cyclodextrin

(sī-klō-dĕks′trĭn)
A molecule made of linked dextrose subunits that can be used in drug delivery in the body. Cyclodextrins have lipid centers surrounded by water-soluble exteriors. This combination allows fat-soluble medicines to be carried through the bloodstream to lipid-rich organs like the brain.
References in periodicals archive ?
Bottcher, Dendritic polyglycerol cyclodextrin amphiphiles and their self-assembled architectures to transport hydrophobic guest molecules, RSC Adv., 4, 61656(2014).
Based on the interactions between albumin and HBCD, this result could also be explained by the structural properties of HBCD and cyclodextrin hydrophobic cavity, the polar outer shell as well as complex tendency to interact with RNA (41).
Yadav, "Effect of cyclodextrin complexation of curcumin on its solubility and antiangiogenic and anti-inflammatory activity in rat colitis model," AAPS PharmSciTech, vol.
Since cyclodextrin reacts with resveratrol to form a stable ester bond, the photostability of the conjugate is improved compared to the parent resveratrol and its inclusion complex.
Population characteristics of cyclodextrin complex stabilities in aqueous solution.
According to Connors and Higuchi [25], the presence of HP-betaCD gave an A-type phase solubility profile typical of soluble cyclodextrin with a positive deviation from linearity (Ap-type, Fig ure 2).
We found out several families were treating their kids with cyclodextrin via the Compassionate Use program, under the Food and Drug Administration (FDA), which refers to the use of investigational drug by patients with life-threatening conditions who could not participate in a clinical trial.
Cyclodextrin, a sugar found in the air freshener Febreze, cleared mouse arteries of cholesterol plaques, Tina Hesman Saey reported in "A sugar can melt away cholesterol," (SN: 5/14/16, p.
Scientists fed mice either a standard Western diet laden with fat or the same diet with the addition of alpha- cyclodextrin supplementation.
"What we did is make the first high-surface-area material made of cyclodextrin [sugar molecules bound together in a ring]," said Will Dichtel, associate professor of chemistry, who led the research, "combining some of the advantages of the activated carbon with the inherent advantages of the cyclodextrin."
The researchers used cyclodextrin to remove cholesterol from milk and cream before manufacturing the cholesterol-reduced cheeses.