On the other hand, idiopathic cyclic edema is a clinical condition related to vessel hypermeability, associated with increased interstitial fluid and characterized by generalized edema .
The objective of this study is to report the clinical control of a case of lipolymphedema associated with idiopathic cyclic edema using calcium dobesilate.
After analysis, the diagnosis was idiopathic cyclic edema, clinical stage II lower limb lymphedema, lipedema stage I and excessive weight.
The present study describes the evolution of edema to clinical stage II lymphedema over time in a patient with lipedema and idiopathic cyclic edema. The clinical stage II lymphedema in this case was reversed using calcium dobesilate.
Idiopathic cyclic edema leads to altered capillary permeability with an overload of the lymphatic system, which is the functional reserve of the venous system.
The diagnosis of idiopathic cyclic edema is basically clinical; there is an increase of more than 800 grams at the end of the day .
Control of cyclic edema is achieved using medications, but these patients cannot ingest excessive quantities of fluids; they should drink only when they are thirsty .
This case is important in the treatment of lymphedema in women because from 5 to 10% of women with lymphedema who seek the clinic have idiopathic cyclic edema. The control of cyclic edema is fundamental; otherwise, control of lymphedema is more difficult because it will be impossible to control the excessive fluid production that leads to an overload of the lymphatic system.
Patients were excluded if the edema was known to be due to nifedipine, intraabdominal malignancy, hypothyroidism, or idiopathic cyclic edema.
The authors of a recent narrative systematic review (1) stated that "most patients with chronic leg edema can be assumed to have venous insufficiency, CHF, or cyclic edema, unless another cause is suspected after a history and physical examination." They also stated that: "pulmonary hypertension and early CHF can both cause leg edema before they become clinically obvious" and reiterate that patients over 45 years of age with edema of unclear cause should have an echocardiogram to rule out pulmonary hypertension.