Cycle-specific agent | definition of cycle-specific agent by Medical dictionary
an agent that has effect in only one part of the cell cycle (S phase) or only when the cell is in a specific part of the cell cycle (for example, methotrexate or nucleoside analogues).
References in periodicals archive
Optisomes' unique sphingomyelin-cholesterol composition is particularly well suited to cell cycle-specific agents
such as vincristine, vinorelbine and topotecan.
The link between drug exposure and anti-tumor efficacy is especially pronounced for cell cycle-specific agents
such as vincristine, vinorelbine and topotecan, which kill tumor cells by interfering with mitosis at a precise step during the cancer cell cycle.