cyclamate


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cyclamate

 [si´klah-māt]
a non-nutritive sweetener; nonprescription use of this substance in the United States was banned when animal testing showed that it may be carcinogenic.

cy·cla·mate

(sī'klă-māt),
A salt or ester of cyclamic acid; the calcium and sodium are noncaloric artificial sweetening agents.

cyclamate

An artificial sweetener 30 times sweeter than sucrose, but with no calorific value. The sodium salt of cyclohexylsulphamic acid. Cyclamate was banned in the UK and USA in 1969 after rats fed the additive throughout their lives developed bladder tumours. In 1995, however, a European panel of experts agreed that the sweetener might safely be used in limited dosage and set a daily intake threshold. Also known as Sucaryl.

cy·cla·mate

(sī'klă-māt)
A salt or ester of cyclamic acid; the calcium and sodium are noncaloric artificial sweetening agents.
References in periodicals archive ?
From the 10th to 14th days of pregnancy, five rats received a daily intraperitoneal injection of sodium cyclamate at a dosage of 60 mg/kg of body weight (Labsynth Ltd., Diadema, SE Brazil) for five days.
Group E served as experimental group and was given sodium cyclamate 60mg/kg/day through oral gavage tube for two months.
As early as 1962, internal Sugar Association memos had acknowledged the potential links between sugar and chronic diseases, but at the time sugar executives had a more pressing problem: Weight-conscious Americans were switching in droves to diet sodas--particularly Diet Rite and Tab--sweetened with cyclamate and saccharin.
Artificial sweeteners such as saccharin, cyclamate, aspartame and sucralose rapidly emerged as low-calorie, tooth-friendly sugar alternatives.
Particularly compelling are the chapters on artificial sweeteners, which blend descriptions of aggressive advertising campaigns with details of backlash against products like saccharin and cyclamate.
Sweeteners with alitame, cyclamate, and steviol glycosides are not approved as food ingredients in the United States but can be found in countries by sheer negligence.
Additives are harmful for human health, especially monosodium glutamate, aspartame, saccharin, sodium cyclamate, sulfites, nitrates, nitrites and antibiotics.
Mentes [2001] demonstrated the cariogenic effect of paediatric medicines, observing variations of pH in plaque produced after rinsing with two versions of the same medicine: one containing only sucrose and another containing saccharine, cyclamate and sorbitol, during a one hour period.
Through the use of a new analytical method, the researchers were able to look for seven different artificial sweeteners (cyclamate, acesulfame, saccharin, aspartame, neotame, neohesperidin dihydrochalcone and sucralose) simultaneously, and show, for the first time, that a number of commonly used artificial sweeteners are present in German waste and surface water.
After fasting blood collection, participants consumed a standard breakfast consisting of 2 slices of whole-meal bread with low-fat margarine and 0.6 L of a green coffee bean extract with artificial sweeteners (sacarine and cyclamate).
"Middle-age and older people still remember the controversy over cyclamate being carcinogenic and its ban," the category manager adds.