cybrid


Also found in: Dictionary, Encyclopedia, Wikipedia.

cy·brid

(sī'brid),
A cell with cytoplasm from two different cells as a result of cell hybridization.
[cell + hybrid]

cybrid

(sī′brĭd′)
n.
1. A cell that has nuclear DNA from one source and cytoplasmic DNA from another, such as a nonhuman animal cell that has had its nucleus replaced by the nucleus of a human somatic cell.
2. A cell line or organism derived from a cybrid cell.
References in periodicals archive ?
MtCIDAS was measured in permeabilized compound and rotenone-treated (22 h + 2 h) cybrid cells containing LHON mutation (11,778) using a bioluminescence method.
This entirely mutation-dependent reduction in energy supply is supported by studies using cybrids carrying LHON mutations as well as peripheral lymphocytes from patients and mutation carriers [13].
Production and characterization of intergeneric diploid cybrids derived from symmetric fusion between Microcitrus papuana Swingle and sour orange (Citrus aurantium).
However, a TBTC concentration [greater than or equal to] 60 nM was required to affect the MIMP of the Awt cybrid (Figure 3).
A decline in complex I-sustained cell respiration and ATP production has been reported in assays performed on isolated mitochondria derived from muscle, Epstein-Barr Virus- (EBV-) transformed leukocytes, peripheral blood mononuclear cells (PBMCs), and cybrids [11-15].
To address cyber threats in CSDP, Estonia is organising in cooperation with the European Defence Agency a strategic table-top cyber-exercise EU CYBRID 2017 for EU Ministers of Defence during their informal meeting in Tallinn on 7 September 2017.
We have been using cybrid studies to evaluate inheritance patterns in RC disorders (10), which requires isolation and evaluation of many clones (>20).
The clonal cybrid cells between the cells lacking mitochondrial DNA and fibroblasts from a patient with the A3243G mutation showed poor respiration, an increased ratio of lactate to pyruvate, and marked defects in the mitochondrial morphology and respiratory chain complex I and IV activities (19).
The origin of the complex I defect in PD has been investigated through cybrid technology (12).