Hypertension was observed in 50% of children who received ACTH whereas only one developed cushingoid appearance
, weight increased, increased appetite, upper respiratory tract infection, cough, pollakiuria, hirsutism, central obesity, nasopharyngitis.
Physical signs of AI can include Cushingoid appearance
: thinning skin, striae, obesity, muscle wasting, and psychiatric disturbance, all of which may indicate prior chronic iatrogenic steroid exposure.
Physically, she exhibited cushingoid appearance
and complained of excessive weight gain and hair growth on the body.
Complications encountered in Group B were namely, Cushingoid appearance
(n=12), GI upset (n=5), recurrence (n=6) and infection (n=3) (Fig.
Additionally, her chronic AIHA came under control after 1 week of MDMP treatment, hemoglobinuria resolved and the bilirubin level decreased after 3 d of MDMP; the only side effect was a mild cushingoid appearance
that regressed after 2 months of the treatment, despite continuation of a relatively low dose of MP (48 mg/d).
Whereas less serious adverse effects (e.g., skin thinning and Cushingoid appearance
) are often of great concern to RA patients, more debilitating serious toxicities, such as vertebral fractures and cataracts, may be initially unrecognized or asymptomatic.
She experienced extreme anxiety, paranoia, agitation, insomnia and behavioural changes, and some associated systemic effects including developing a cushingoid appearance
, alopecia, systemic and ocular hypertension, nausea and hypercholesterolemia.
* Dermatoiogical changes can occur with steroid therapy, including a redistribution of subcutaneous fat causing the cushingoid appearance
of central obesity, hump back, and moon face.
Physical examination revealed a slightly cushingoid appearance
and the patient was incontinent of urine.
Complications included steroid-related side effects--such as hyperphagia, a cushingoid appearance
, and a herpetic esophageal ulcer--in 11 of the patients treated with prednisone.
In a patient of cushingoid appearance
, a 24-hour urine cortisol test or low-dose dexamethasone suppression test is useful.