Tzoulaki I, Molokhia M, Curcin
V, Little MP, Millett CJ, Ng A, et al.
curcas seeds contain a toxalbumin, curcin
, which is 1 000 times less toxic than ricin found in Jatropha multifida seeds.
Structure prediction and binding sites analysis of curcin
protein of Jatropha curcas using computational approaches.
The toxic or anti-nutrient compounds isolated from JDC include curcin
, phorbol esters, phytate, curcalonic acids, flavanoids, vitexine and isovitexine (3,4).
Millett C, Bottle A, Ng A, Curcin
V, Molokhia M, Saxena S, Majeed A.
management systems ICTs Bibliographical References Workflow Digiampietri (2007); Curcin
& management systems Ghanem (2009); Hacievliyagil (2007).
the cyclic triterpenes stigmasterol, curcacycline A, and curcin
(Sachdeva et al.
Although the seed cake meal is rich in protein, it is toxic to rats, mice, ruminants and humans due to the presence of antinutritional factors such as phorbol esters, curcin
, trypsin inhibitors, lectin, [5, 6, 8, 10-12], .
Cloning, Expression, and Antitumor Activity of Recombinant Protein of Curcin
For example, Curcin
, a kind of type I ribosome- inactivating protein with anti-tumor and anti-virus activity, is first found from the seeds of Jatropha (Stirpe et al.
Another possibility would be higher presence of toxins (phytates, tripsin inhibitors, curcin
and forbol esters) present in physic nut cake (MAKKAR et al.
Due to the presence of several toxins including curcascine or curcin
, phorbol esters, saponins, protease inhibitors and phytates, the seed or the oil cannot be used for human or animal consumption (Data et al.