cumulative effect

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a result produced by an action.
additive effect the combined effect produced by the action of two or more agents, being equal to the sum of their separate effects.
adverse effect a symptom produced by a drug or therapy that is injurious to the patient.
Bainbridge effect Bainbridge reflex.
Bohr effect decreased affinity of hemoglobin for oxygen caused by an increase of carbon dioxide; the oxyhemoglobin dissociation curve is displaced to the right because of higher partial pressure of carbon dioxide and lower pH. See also Haldane effect.
The Bohr effect causing a shift to the right in the oxyhemoglobin dissociation curve.
Crabtree effect the inhibition of oxygen consumption on the addition of glucose to tissues or microorganisms having a high rate of aerobic glycolysis; the converse of the Pasteur effect.
cumulative effect the action of a drug or treatment resulting from repeated use.
Doppler effect see doppler effect.
experimenter e's demand characteristics.
extrapyramidal e's the side effects caused by neuroleptic medications, including dystonias, parkinsonism, akathisia, and tardive dyskinesia.
Haldane effect increased oxygenation of hemoglobin promotes dissociation of carbon dioxide; see also Bohr effect.
Hawthorne effect a psychological response in which the subjects in a research study change their behavior simply because they are subjects in a study, not because of the research treatment.
heel effect variation in x-ray beam intensity and projected focal spot size along the long axis of the x-ray tube from cathode to anode.
parallax effect the position of the image on each emulsion of dual emulsion film; it is accentuated by tube-angled x-ray techniques.
Pasteur effect the decrease in the rate of glycolysis and the suppression of lactate accumulation by tissues or microorganisms in the presence of oxygen.
photoelectric effect ejection of electrons from matter as a result of interaction with photons from high frequency electromagnetic radiation, such as x-rays; the ejected electrons may be energetic enough to ionize multiple additional atoms.
placebo effect the total of all nonspecific effects, both good and adverse, of treatment; it refers primarily to psychological and psychophysiological effects associated with the caregiver-patient relationship and the patient's expectations and apprehensions concerning the treatment. See also placebo.
position effect in genetics, the changed effect produced by alteration of the relative positions of various genes on the chromosomes.
pressure effect the sum of the changes that are due to obstruction of tissue drainage by pressure.
proarrhythmic effect any new, more advanced form of arrhythmia caused by an antiarrhythmic agent, especially those that produce hemodynamically important symptoms. These arrhythmias occur less than 30 days after initiation of treatment and are not due to a new event such as acute myocardial infarction or hypokalemia.
side effect a consequence other than that for which an agent is used, especially an adverse effect on another organ system.
Somogyi effect see somogyi effect.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

cu·mu·la·tive ef·fect

the condition in which repeated administration of a drug may produce effects that are more pronounced than those produced by the first dose.
Synonym(s): cumulative action
Farlex Partner Medical Dictionary © Farlex 2012

cu·mu·la·tive ef·fect

(kyūm'yŭ-lă-tiv e-fekt')
The condition in which repeated administration of a drug may produce effects that are more pronounced than those produced by the first dose.
Synonym(s): cumulative action.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
The point to be made to legislators, leadership and the governor is that a comprehensive view of what is being proposed needs to be undertaken so businesses do not suffer from the cumulative effect of hundreds of proposals.
If it is impracticable to determine the cumulative effect of applying a change in accounting principle to any prior period, the new accounting principle shall be applied as if the change was made prospectively as of the earliest date practicable.
High school and college male athletes do not appear to suffer cumulative effects from one to two previous concussions, according to a cross-sectional study of 867 athletes.
154 requires retrospective application of the direct effects of an accounting change, unless it is impracticable to determine either the cumulative effect or the period-specific effects of the change (see "The Change Game," JofA, Dec.05, page 67).
However, because the research did not address the cumulative effect of water variations, if a green sand system is not rapidly replaced, the cumulative effect of water additions, could, over time, have an effect on your sand system.
The cumulative effect of applying the interpretation's provisions will be reported as a change in accounting principle as of the end of the period in which adopted.
I think books have a cumulative effect. But history books probably have had the biggest impact, because they've allowed me to learn more about life based on what so many people have already been through.
"Analyzing and computing the cumulative effect of the accounting change to implement the far-reaching effects of a fundamental change in the recognition of all tax positions as well as making the necessary process control changes to comply with the documentation and testing requirements of section 404 of the Sarbanes-Oxley Act will require substantial time and resources for all companies, especially those operating on a global basis." Since companies "would require more time to understand [the FASB's proposed interpretation], reevaluate all tax positions for all open tax years, review the effect of the adoption of the Interpretation with their audit firms," the interpretation should not be effective until the later of December 15, 2006, or six months following its adoption.
However, how many non-prejudicial errors will appellate courts allow before they recognize that a number of non-prejudicial errors can have a 'cumulative effect' requiring the reversal of a judgment of a trial court?
For example, they note that a critical dimension of this interaction is "to explore the cumulative effect of earlier life events on later ones and to investigate how the timing of one event--child birth for example--might shape the subsequent life trajectory of any one individual" (pg.
The cumulative effect of solving many small problems is significant.
So it will come as no surprise that some camps have responded to growing property and casualty insurance premiums and the cumulative effect of increased general business expenses by electing to drop Accident and Sickness Medical Insurance entirely.

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