coumarin

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coumarin

[koo´mah-rin]

1. a principle extracted from the tonka bean, from which several anticoagulants are derived that inhibit hepatic synthesis of vitamin K–dependent coagulation factors.

2. any of these derivatives.

cou·ma·rin

(kū'mă-rin),

1. A general descriptive term applied to anticoagulants and other drugs derived from dicumarol, a component of the Tonka bean.

2. A fragrant neutral principle obtained from the Tonka bean, Dypterix odorata, and made synthetically from salicylic aldehyde; it is used to disguise unpleasant odors.

Synonym(s): coumaric anhydride, cumarin

[coumarou, native name of Tonka bean]

coumarin

/cou·ma·rin/ (koo´mah-rin)

1. a principle extracted from the tonka bean; it contains a factor, dicumarol, that inhibits hepatic synthesis of vitamin K–dependent coagulation factors, and a number of its derivatives are used as anticoagulants in treating disorders characterized by excessive clotting.

2. any of these derivatives or any synthetic compound with similar activity.

coumarin

(ko͞o′mər-ĭn)

A fragrant crystalline compound, C₉H₆O₂, present in tonka beans and produced synthetically for use as a fragrance. Coumarin has been banned as a food additive in the United States because it can be toxic in large amounts.

cou′ma·ric (-mər-ĭk) adj.

coumarin

[ko̅o̅′mərin]

a class of orally active anticoagulant agents with warfarin as its prototype.

indications It is prescribed for prophylaxis and treatment of thrombosis and embolism.

contraindications Known hypersensitivity to the drug prohibits its use. It is not prescribed to patients who are at risk for hemorrhage or who are pregnant.

adverse effects The most serious adverse reaction is hemorrhage. Many other drugs interact with this drug to increase or decrease its effect.

cou·ma·rin

(kū'mă-rin)

Fragrant neutral principle obtained from the Tonka bean, Dypterix odorata, and also made synthetically from salicylic aldehyde; used to disguise unpleasant odors.

coumarin,

n C₉H₆O, derived from a variety of sources, including tonka bean and sweet clover; may also be artificially manufactured.

Coumarin.

cou·ma·rin

(kū'mă-rin)

A general descriptive term applied to anticoagulants and other drugs derived from dicumarol.

coumarin

1. a principle extracted from the tonka bean, from which several anticoagulants are derived, that inhibits hepatic synthesis of vitamin K-dependent coagulation factors.

2. any of these derivatives.

3. see also dicoumarol.

References in periodicals archive ?

extract) were analyzed in order to quantify nuzhenide, GI-3 and identify the main cumarins present in the extract (Fig.

A Fraxinus excelsior L. seeds/fruits extract benefits glucose homeostasis and adiposity related markers in elderly overweight/obese subjects: A longitudinal, randomized, crossover, double-blind, placebo-controlled nutritional intervention study

Chemical substances, such as terpenes, phenolic compounds, cumarins, flavonoids, alkaloides, glycosides, tannins and quinones, originating from the secondary metabolisms of plants could initiate beneficial or harmful effects on other plants or other organisms (PINA- RODRIGUES; LOPES, 2001).

Allelopathy in five species of Erythroxylum/Alelopatia em cinco especies de Erythroxylum

The principal secondary metabolites of the whole ethanolic extract and fractions obtained of this briophyta were terpens, polyphenols, cumarins, glycosilated molecules and sucrose.

Analisis fotoquimico y de actividad biologica del musgo Polytrichum juniperinum

A number of investigators have shown that cumarins, flavonoids, terpenoids and a host of other secondary plant metabolites, including arginine and glutamic acid exhibit antidiabetic properties (Ross, 2001).

A novel steroid from Elephantopus scaber L. an ethnomedicinal plant with antidiabetic activity

Main ingredients of EPs 7630 are cumarins, procyanides, tannins and phenol carboxylic acids.

A new approach to pharmacological effects on ciliary beat frequency in cell cultures--exemplary measurements under Pelargonium sidoides extract (EPs 7630)