The cells range from flat to cuboidal
to columnar and have clear or eosinophilic cytoplasm, or a combination of both, with moderate to severe cytologic atypia and frequent brisk mitotic activity.
The most common types were pseudostratified cylindrical ciliated epithelium with goblet cells (figures 2 and 3), stratified cuboidal
epithelium (figures 4 and 5), and stratified squamous nonkeratinized epithelium (figures 6 and 7).
Gene expression and clonality analysis of the androgen receptor and phosphoglycerate kinase genes in polygonal cells and cuboidal
cells in so-called pulmonary sclerosing hemangioma.
Pathologic Features Differentiating Lepidic Adenocarcinoma From Reactive Hyperplasia Features favoring lepidic neoplasm Grossly mass lesion Sharp interface of pneumocyte proliferation Sharp interface of interstitial inflammation/fibrosis Monotonous cuboidal
or low columnar pneumocyte proliferation Features favoring reactive proliferation Major Indistinct transitions Cellular size variation Multinucleation Cilia No intranuclear inclusions Retained lung architecture Minor Absence of macronucleoli despite nuclear atypia Absence of atypical mitoses despite nuclear atypia
HE stain of a section of the right ovarian papillary serous cystadenoma showing cuboidal
epithelium (arrow head), papillary projections (long arrow) and connective tissue stroma (short arrow).
Caption: FIGURE 3: Pathology: There is a benign cystic inclusion lined by cuboidal
to columnar cells with Mullerian differentiation showing ciliated columnar, secretory, and intercalated cells.
The mass was composed of cuboidal
and polygonal cells arranged in elongated tubular structures with multifocal papillary projections into the lumen supported by a fine fibrovascular stroma (Figure 1C-D).
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12-year-old specimen stained with Masson's Trichrome shows bilaminar ductal epithelium with basal cuboidal
and luminal columnar cells with darkly stained nuclei (Fig: 6).
Out of thirty colonies, eleven colonies showed bipyramidal or bipyramidal with cuboidal
crystalline inclusions (Fig 1).
Main confirmatory test for diagnosis in our setup is liver biopsy which shows bands of fibrous tissues often containing linear or circular spaces lined by cuboidal
The neoplastic cells were single to double layered, cuboidal
to low columnar epithelial cells and abundant eosinophilic cytoplasm and lumen contained copper coloured secretions.