digitoxin
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digitoxin
[dij″ĭ-tok´sin]a cardiotonic glycoside obtained from Digitalis purpurea and other species of the same genus; used in the treatment of congestive heart failure. It has a slowly developing action and slow elimination. Parenteral solutions should be diluted when given intravenously.
dig·i·tox·in
(dij'i-tok'sin),A cardioactive glycoside obtained from the leaves of Digitalis purpurea; it is more completely absorbed from the gastrointestinal tract than is digitalis. Largely eliminated by hepatic metabolism.
Synonym(s): crystalline digitalin
digitoxin
/dig·i·tox·in/ (-tok´sin) a cardiotonic glycoside from Digitalis purpurea and other Digitalis species; used similarly to digitalis.digitoxin
(dĭj′ĭ-tŏk′sĭn)n.
A highly active glycoside, C41H64O13, derived from digitalis and prescribed in the treatment of certain cardiac conditions.
digitoxin
[dij′itok′sin]
a cardiac glycoside obtained from leaves of Digitalis purpurea. Digitoxin differs in many ways from digoxin, including having a far greater half-life and a different route of elimination.
indications It is prescribed in the treatment of congestive heart failure and certain cardiac arrhythmias.
contraindications Ventricular fibrillation, ventricular tachycardia, or known hypersensitivity to this drug prohibits its use.
adverse effects The most serious adverse reactions are cardiac arrhythmias and heart block, disorientation, and visual disturbances.
digitoxin
Cardiology A cardiac glycoside used like digoxin, which binds more strongly to proteins, but for a similar pharmacologic effect, requires a 10-fold greater concentrationdig·i·tox·in
(dij'i-tok'sin)A cardioactive glycoside obtained from the leaves of Digitalis purpurea; it is more completely absorbed from the gastrointestinal tract than is digitalis. Also called crystalline digitalin.
digitoxin
a poisonous glycoside contained in digitalis, an extract from the foxglove; it is a powerful heart stimulant.digitoxin
(dij´itok´sin),
n brand names: Crystodigin, Digitaline;
drug class: cardia glycoside;
action: inhibits the formation of sodium-potassium ATPase, which makes more calcium available for contractile proteins;
uses: congestive heart failure (CHF), atrial fibrillation, paroxysmal atrial flutter, atrial tachycardia.
n brand names: Crystodigin, Digitaline;
drug class: cardia glycoside;
action: inhibits the formation of sodium-potassium ATPase, which makes more calcium available for contractile proteins;
uses: congestive heart failure (CHF), atrial fibrillation, paroxysmal atrial flutter, atrial tachycardia.
digitoxin
a cardiotonic glycoside obtained from Digitalis purpurea and other species of the same genus; used in the treatment of congestive heart failure.