Diagnosis of cryptogenic cirrhosis
was made on the basis of exclusion of all known causes of cirrhosis.
The etiology of liver failure was defined as: enolic cirrhosis, hepatitis C virus (HCV), cryptogenic cirrhosis
, and 1 case of HPS due to non-cirrhotic portal hypertension of presinusoidal prehepatic origin.
The pathologic examination of the explanted liver confirms the pre-transplant diagnosis, and can identify additional comorbidities as well as causes of cryptogenic cirrhosis
, especially for etiologies such as biliary diseases that may be heterogeneous and not sampled on liver biopsies (fig-2).
The findings are also reliant on data coding and of course it is possible that patients with NASH are included in the NAFLD group, and non-NASH cirrhosis could be included in the cryptogenic cirrhosis
Etiology of liver cirrhosis from Southern Iran Wilson disease 33% Biliary atresia 28% Cryptogenic cirrhosis
21% Autoimmune hepatitis 18% Note: Table made from pie chart.
is a diagnosis made after excluding identifiable causes, including viral hepatitis, autoimmune hepatitis, and metabolic liver diseases.
Most (11 of 12) NAFLD transplant cases were associated with the clinical diagnosis of cryptogenic cirrhosis
In few cases the cause may not be found, the so called cryptogenic cirrhosis
But the guidelines also specifically caution against using vitamin E in patients with NASH and diabetes, patients with NAFLD who have not undergone a liver biopsy, patients with NASH and cirrhosis, and those with cryptogenic cirrhosis
The mum–of–two was diagnosed with cryptogenic cirrhosis
in 2002 after the birth of her first daughter Niamh.
foetus peritonitis in a 52-year-old man with common variable immunodeficiency, rheumatoid arthritis, splenectomy, and cryptogenic cirrhosis
These findings are consistent with previously published reports in the United States in which HCV (55%), HBV (17%), alcoholic (9%), and cryptogenic cirrhosis
(7%) are significant causes of HCC.