We summarize the main subjects in explaining the cryptochrome
magnetoreception and point out that the animal's genius radical pair mechanism reminds us of a new chemical magnetic detection mechanism, which is different from current magnetic detection technology.
1998 Conditional synergism between cryptochrome
1 and phytochrome B is shown by the analysis of phyA, phyB, and hy4 simple, double, and triple mutants in Arabidopsis.
Now scientists have found in their studies with mice that cryptochrome
has another function -- regulating a process called " gluconeogenesis", in which our bodies supply glucose to keep the brain and other organs and cells functioning.
It really says that cryptochrome
, which is linked to animals' circadian clock, is also involved in a living animal's response to magnetic fields," says study coauthor Steven M.
Antagonistic actions of Arabidopsis cryptochromes
and phytochrome B in the regulation of floral induction.
's effects could lead to better depression treatments and fewer accidents during night shifts.
Sancar, "Dual modes of CLOCK:BMAL1 inhibition mediated by Cryptochrome
and Period proteins in the mammalian circadian clock," Genes & Development, vol.
The identity of several core circadian genes that are responsible for producing these rhythms has been revealed in a number of invertebrates and vertebrates  and includes period, clock, cryptochrome
, cycle, timeless, and other accessory genes.
The two proteins form heterodimers that activate transcription of the genes coding for Period (PER) and Cryptochrome
In plants, light signals are first perceived by the photoreceptors containing phytochrome (PhyA, PhyB, PhyC, PhyD and PhyE) and cryptochrome
, which process the physical signals.
2000) combine (i.e., heterodimerize) to stimulate the transcription of target circadian genes including period (Per) and cryptochrome
(Cry) (i.e., Perl to Per3 and Cryl and Cry2) as well as a host of other clock-controlled genes.
The Salk team found that the absence of a key circadian clock component called cryptochrome
(CRY) leads to the activation of a signaling system that elevates levels of inflammatory molecules in the body.