Clinical practice guidelines on the use of blood components (red blood cells, platelets, fresh frozen plasma, cryoprecipitate
In the pediatric ICU the patient received several transfusions with platelets, cryoprecipitate
, and fresh frozen plasma to manage DIC.
Considering that the patient also had a massive hemorrhage in the form of menstruation, FFP and cryoprecipitate
were also administered at the same time of anti-coagulation therapy to keep a fibrinogen activity level more than 1.0g/L.
It also assumed that NATO would adopt SC2i's MTP blood product ratio of 16.5 units of RBC, 9.8 units of FFP, 0.9 apheresis of platelets, and 7.2 units of cryoprecipitate
as its standard massive transfusion protocol, rather than the U.S.
Intraoperative blood product utilization was very common in this group of patients, although only the use of fresh frozen plasma (FFP) and cryoprecipitate
was significantly associated with PPMV (Table 2).
The acute bleeding can be controlled by infusion of cryoprecipitate
, vWF-containing factor VIII (FVIII) concentrates (haemate-p), or desmopressin.
, or both maybe used to replenish fibrin and clotting factors.
The key indicators were related to facilities of blood transfusion services, blood policy, legislation governing transfusion, funding of blood safety, voluntary, nonremunerated blood donations, of blood components preparation (e.g., one whole blood donation can be used for the preparation of units of red cell concentrate, fresh frozen plasma, platelets, and cryoprecipitate
), screening of blood donations for TTIs, guidelines on the rational use of blood and blood products, establishment of national haemovigilance systems, and so on.
Most blood banks split the whole blood into two or more components such as red cell concentrate, platelet concentrate, fresh frozen plasma or cryoprecipitate
and fibrin glue.
Supportive care included transfusion of packed red blood cells, platelets, cryoprecipitate
, and fresh frozen plasma.
 In particular, a profound drop in fibrinogen levels develops.!12 This is one of the indications for the use of cryoprecipitate
. [2 Since this product was not available at the base hospital, and it was not possible to measure the fibrinogen level there, FDP was a good choice.
Total collections and transfusions of whole blood, whole blood derived (WBD) RBC, platelet, plasma, and cryoprecipitate
units (including total numbers of blood components imported from the continental United States), as well as RBC, platelet, and plasma units collected via apheresis ([paragraph]) methods were tabulated.