cryofibrinogen


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cryofibrinogen

 [kri″o-fi-brin´o-jen]
an abnormal fibrinogen that precipitates at low temperatures and redissolves at 37° C.

cry·o·fi·brin·o·gen

(krī'ō-fī-brin'ō-jen),
An abnormal type of fibrinogen very rarely found in human plasma; it is precipitated on cooling but redissolves when warmed to room temperature.

cry·o·fi·brin·o·gen

(krī'ō-fī-brin'ō-jen)
An abnormal type of fibrinogen very rarely found in human plasma; precipitated on cooling, but redissolves when warmed to room temperature.
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A series of serum laboratory assessments were obtained including; a CBC with peripheral smear, cryoglobulins, cryofibrinogens, C-reactive protein (CRP), protein S activity and antigen, anti-neutrophil cytoplasmic antibodies, lupus anticoagulant, activated protein C (APC) resistance assay, prothrombin gene mutation assay, factor V Leiden assay, factor VIII activity level and a D-dimer assay.
There are 2 types of cryoproteins, cryoglobulins and cryofibrinogens. Cryoglobulins are immunoglobulins that precipitate both from serum and plasma, whereas cryofibrinogens, which consist of fibrinogen-fibrin complexes, precipitate only from plasma (1).