We recommend that clinicians involved in the care of patients with crush injury
from sjambok beating adopt the system we propose of early risk stratification using the initial VB, without the need for urine dipstick analysis or serum electrolyte analysis, based on the VB categories shown in Table 6.
Groups 8: In this group subcutaneous injection of vitamin E at a dose of 100 mg/kg was performed after induction of a crush injury in sciatic nerve and served as vitamin E groups.
Group 9: In this group subcutaneous injection of normal saline was done for 10 consecutive days after surgically-induced crush injury in sciatic nerve and served as crush plus normal saline group.
Crush injury produced severe changes in the sciatic nerve, including swelling of myelin sheet, vacuolization and myelin ellipsoids (Figs.
In the present study, safranal and vitamin E suppressed cold and mechanical allodynia due to sciatic nerve crush injury.
Our initial studies investigated the therapeutic potential of ES in nerve regeneration following a rat facial nerve crush injury because of ES's enhancing effects on the morphological and functional properties of neurons [1-4].
It has also been reported that, following sciatic nerve crush injury in rats, administering ES accelerates the appearance of the toe-spreading reflex, a sensitive indicator of the onset of motor recovery , further supporting the concept that ES enhances early regeneration events that initiate sprout formation.
Therefore, the present experiment also studied whether daily ES was necessary or whether a shorter number of sessions would be sufficient to enhance regeneration following a facial nerve crush injury.
We have previously explored the role of inflammation on functional recovery by treating with the corticosteroid prednisone following an intratemporal facial nerve crush injury .