One systematic review that looked at the efficacy of metoclopramide for gastroparesis identified one small RCT and 3 smaller placebo-controlled crossover trials
. (1) The RCT (using 10 mg of metoclopramide after meals and at bedtime) found consistent improvement in the sense of fullness over 3 weeks of therapy, with reduction of nausea at one and 3 weeks, but not at 2 weeks.
Moderate evidence--In a crossover trial
, Yigiter et al.
A randomized 2 x 2 crossover trial
was designed with one group randomly assigned to a normal-to-low-salt bread sequence and the other group to a low-to-normal-salt bread sequence (27).
Both aloe vera gel and whole leaf aloe were tested in the random crossover trial
, with the gel demonstrating the strongest results in promoting the absorbance of vitamins C and B12.
An unpublished, placebo-controlled, double-blind crossover trial
of 5 mg of melatonin on 16 children with autism or Asperger's syndrome found increases in total sleep time, shorter sleep latencies, and significant improvements in child functioning.
But the company's random-ized crossover trial
in 48 HIV-negative volunteers who took Lexiva for two weeks with Nexium, and later for two weeks without, found that this did not happen, at least with the 20 mg dose of Nexium tested (the drug is supplied in 20 and 40 mg doses)--whether or not the Lexiva was "boosted" with a small dose of Norvir.
The program was designed as a self-help and home-based program over 6 weeks and compared to standard care within a randomised crossover trial
in 16 patients with moderate heart failure NYHA class II-III.
This point emerges in Kulczycki and colleagues' short-term crossover trial
, in which the majority of users rated the female condom as much less acceptable than the male condom on a wide range of features.
Researchers conducted a randomized, crossover trial
of glicazide and metaformin in 36 patients who had either type 2 diabetes or diabetes caused by a genetic mutation HNF-la.
 Jacobsson et al published the results of a double-blind, placebo-controlled, crossover trial
The students, all regular coffee drinkers, were given grapefruit juice with or without caffeine during two different medical school exams in a double blind, placebo-controlled, randomized crossover trial
. The combination of caffeine and a stressful situation caused blood pressure to increase significantly, with 48% of participants registering average systolic readings of 140mm HG or higher.
Kelvin Robertson, from The Townsville Hospital in Australia, and colleagues conducted a preplanned interim analysis of a randomized, double-dummy crossover trial
of PGB and GBP for management of CS.