cross-tolerance


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cross-tolerance

 [kros´tol-er-ans]
extension of the tolerance for a substance to others of the same class, even those to which the body has not been exposed previously.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

cross-tolerance

(krôs′tŏl′ər-əns, krŏs′-)
n.
Tolerance or resistance to an effect or effects of a compound as a result of tolerance previously developed to a pharmacologically similar compound.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

cross-tol·er·ance

(kraws tol'ĕr-ăns)
The resistance to one or more effects of a compound as a result of tolerance developed to a pharmacologically similar compound.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

cross-tol·er·ance

(kraws tol'ĕr-ăns)
Resistance to one or several effects of a compound as a result of tolerance developed to a pharmacologically similar compound.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
Due to the observation that A20 is a key molecule in the establishment of TNF/LPS cross-tolerance [6], its importance within TNF tolerance has also been assessed.
Framework of Addiction Interaction Disorders (1) Cross-tolerance (a) "A simultaneous increase of addictive behaviour in two or more addictions", or (b) when one addictive behaviour is substituted for another and there is a higher-than-expected tolerance for the new behaviour.
Chronic alcohol treatment can produce not only tolerance to the effects of alcohol but also cross-tolerance to the effects of nicotine.
This illustrates that, under the range of operating conditions used in this study, cross-tolerance is insignificant in predicting viability loss.
As mentioned earlier, acclimation to some stresses has also been found to provide cross-tolerance to other stresses.
The sedative-hypnotic drugs, including alcohol and benzodiazepines, have cross-tolerance and dependence to one another so that any may be substituted for the other.
Finally, to gain insights into the cytokine patterns and potential cross-tolerance, the effect of LTA pretreatment was examined in CpG/D-galN and R848/D-galN mice.
Another mechanism that may contribute to alcohol-nicotine interactions is cross-tolerance to the effects of both drugs.
The role of calcium and activated oxygen as signals for controlling cross-tolerance. Trends Plant Sci., 5: 241246
Different opioids bind slightly differently to receptors, and incomplete cross-tolerance is common, she noted.
These mechanisms include genes that are involved in regulating certain brain chemical systems; neurobiological mechanisms, such as cross-tolerance and cross-sensitization to both drugs; conditioning mechanisms, in which cravings for alcohol or nicotine are elicited by certain environmental cues; and psychosocial factors (e.g., personality characteristics and coexisting psychiatric disorders).