cross-tolerance

Also found in: Dictionary, Encyclopedia, Wikipedia.

cross-tolerance

[kros´tol-er-ans]

extension of the tolerance for a substance to others of the same class, even those to which the body has not been exposed previously.

cross-tolerance

/cross-tol·er·ance/ (kros´tol-er-ans) extension of the tolerance for a substance to others of the same class, even those to which the body has not been exposed previously.

cross-tolerance

(krôs′tŏl′ər-əns, krŏs′-)

Tolerance or resistance to an effect or effects of a compound as a result of tolerance previously developed to a pharmacologically similar compound.

cross-tolerance

a tolerance to other drugs that develops after exposure to a different agent. An example is the cross-tolerance that develops between alcohol and barbiturates.

cross-tol·er·ance

(kraws tol'ĕr-ăns)

The resistance to one or more effects of a compound as a result of tolerance developed to a pharmacologically similar compound.

cross-tol·er·ance

(kraws tol'ĕr-ăns)

Resistance to one or several effects of a compound as a result of tolerance developed to a pharmacologically similar compound.

cross-tolerance,

n See tolerance, cross-.

Mentioned in ?

References in periodicals archive ?

Cross-tolerance associated with temperature and salinity stress during germination of barley seeds.

Response to temperature stress of reactive oxygen species scavenging enzymes in cross-tolerance of barley seed germination.

Induction of water deficit tolerance by cold shock and salicylic acid during germination in the common bean/Inducao da tolerancia ao estresse hidrico por choque frio e acido salicilico durante a germinacao em feijoeiro

As mentioned earlier, acclimation to some stresses has also been found to provide cross-tolerance to other stresses.

Review: abiotic stress sensing and GABA response in plants

Alternatively, cross-tolerance between the two drugs may reduce the drugs' aversive effects and motivate people to use more of the drugs in order to achieve the same rewarding effects.

The possibility that tolerance and cross-tolerance to the effects of alcohol and nicotine contribute to their co-use will be discussed, as will the evidence for a shared genetic predisposition to concurrently use or abuse alcohol and nicotine.

Biological processes underlying co-use of alcohol and nicotine: neuronal mechanisms, cross-tolerance, and genetic factors

These mechanisms include genes that are involved in regulating certain brain chemical systems; neurobiological mechanisms, such as cross-tolerance and cross-sensitization to both drugs; conditioning mechanisms, in which cravings for alcohol or nicotine are elicited by certain environmental cues; and psychosocial factors (e.

Concurrent alcohol and tobacco dependence: mechanisms and treatment

Different opioids bind slightly differently to receptors, and incomplete cross-tolerance is common, she noted.

Pearls offered for end-of-life pain treatment

If confirmed in humans, this phenomenon, which is called cross-tolerance, may have important implications for the combined use of nicotine and alcohol in humans.